Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | CAPN1 | P07384 | 12/20 | 0.43 |
| ▸ | CCR1 | P32246 | 1/20 | 0.43 |
| ▸ | CAPNS1 | P04632 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8408032 | 0.90 | CAPN1 (0.51) | CAPN1CAPNS1NPC1RAB9A | |
| SCHEMBL8810535 | 0.89 | CAPN1 (0.52) | CAPN1CAPNS1ALDH1A1 | |
| SCHEMBL8809572 | 0.89 | CAPN1 (0.50) | CAPN1CCR1CAPNS1 | |
| SCHEMBL8807780 | 0.88 | TAS1R3 (0.46) | CAPN1CAPNS1TAS1R3TAS1R1ALDH1A1 | |
| SCHEMBL8812425 | 0.87 | CAPN1 (0.53) | CAPN1CAPNS1TAS1R3TAS1R1ALDH1A1 | |
| SCHEMBL8809378 | 0.87 | HDAC4 (0.42) | POLBCAPN1CAPNS1NPC1LMNA | |
| SCHEMBL8810413 | 0.85 | TAS1R3 (0.49) | CAPN1TAS1R3TAS1R1NPC1RAB9A | |
| SCHEMBL8810404 | 0.85 | CAPN1 (0.46) | POLBCAPN1CAPNS1TAS1R3TAS1R1 | |
| SCHEMBL8404222 | 0.85 | CAPN1 (0.47) | HTTPOLBCAPN1CCR1CAPNS1 | |
| SCHEMBL8812456 | 0.83 | CASP1 (0.52) | CAPN1CCR1CAPNS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0925786-A1 | REMEDIES FOR ISCHEMIC DISEASES | MITSUBISHI CHEMICAL CORPORATION (JP) | 1999-06-30 | — | — | EP | disclosed |
| EP-0810221-A1 | OXYGEN-CONTAINING HETEROCYCLIC DERIVATIVES | MITSUBISHI CHEMICAL CORPORATION (JP) | 1997-12-03 | — | — | EP | disclosed |