Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 6/20 | 0.44 |
| ▸ | MMP2 | P08253 | 8/20 | 0.44 |
| ▸ | MMP9 | P14780 | 7/20 | 0.44 |
| ▸ | MMP1 | P03956 | 7/20 | 0.44 |
| ▸ | MMP13 | P45452 | 6/20 | 0.44 |
| ▸ | MMP8 | P22894 | 3/20 | 0.44 |
| ▸ | MMP7 | P09237 | 1/20 | 0.42 |
| ▸ | MMP12 | P39900 | 1/20 | 0.42 |
| ▸ | BMP1 | P13497 | 3/20 | 0.41 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8400808 | 0.88 | BMP1 (0.44) | MMP3MMP2MMP9MMP1MMP13 | |
| SCHEMBL8404582 | 0.85 | MMP9 (0.41) | MMP3MMP2MMP9MMP1MMP13 | |
| SCHEMBL8012967 | 0.84 | MMP9 (0.51) | MMP3MMP2MMP9MMP1MMP13 | |
| SCHEMBL8658468 | 0.82 | BMP1 (0.48) | MMP3MMP2MMP9MMP1MMP13 | |
| SCHEMBL8014840 | 0.82 | MMP3 (0.46) | MMP3MMP2MMP9MMP1MMP13 | |
| SCHEMBL8004745 | 0.82 | MMP9 (0.51) | MMP3MMP2MMP9MMP1MMP13 | |
| SCHEMBL8014648 | 0.82 | MMP9 (0.51) | MMP3MMP2MMP9MMP1MMP13 | |
| SCHEMBL8405651 | 0.82 | ALDH1A1 (0.49) | MMP3MMP2MMP1MMP13MMP8 | |
| SCHEMBL8403382 | 0.81 | MMP9 (0.45) | MMP3MMP2MMP9MMP1MMP13 | |
| SCHEMBL8012934 | 0.81 | BMP1 (0.51) | MMP3MMP2MMP9MMP1MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0922030-A1 | ARYLSULFONYLAMINO HYDROXAMIC ACID DERIVATIVES | PFIZER INC. (US) | 1999-06-16 | — | — | EP | disclosed |
| WO-1998007697-A1 | ARYLSULFONYLAMINO HYDROXAMIC ACID DERIVATIVES | PFIZER INC. (US) | 1998-02-26 | — | — | WO | disclosed |