SCHEMBL8405285

SCHEMBL8405285

CCCc1cc[c]c(OC)c1OC

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HMGCR P04035 1/20 0.34
AOC3 Q16853 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8895951 0.85 PTGS2 (0.32)
SCHEMBL6023394 0.81 HMGCR (0.34) HMGCRAOC3
SCHEMBL2439840 0.79 MAPT (0.37)
SCHEMBL8408163 0.77 HMGCR (0.32) HMGCR
SCHEMBL6504160 0.76 HMGCR (0.35) HMGCR
SCHEMBL8405349 0.74 ALOX5 (0.34)
SCHEMBL6024208 0.73
SCHEMBL10600231 0.71 ALOX5 (0.43) HMGCR
SCHEMBL8408811 0.70 NOS2 (0.37)
SCHEMBL8405936 0.70 HMGCR (0.34) HMGCR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5952504-A REACTING A SULFONATED, HALOGENATED OR PHOSPHONATED 1,7-NAPHTHYRIDINE COMPOUNDS WITH AN AROMATIC AMINE DERIVATIVE; ANTIULCER AGENT YUNGJIN PHARMACEUTICAL COMPANY, LTD. (KR) 1999-09-14 US disclosed
EP-0843677-A1 4-AMINO-3-ACYLNAPHTHYRIDINE DERIVATIVES YUNGJIN PHARMACEUTICAL CO., LTD. (KR) 1998-05-27 EP disclosed