SCHEMBL8405341

SCHEMBL8405341

CCCCCCC(C)(c1ccc(Oc2ccccc2N2C(=O)C=CC2=O)cc1)c1ccc(Oc2ccccc2N2C(=O)C=CC2=O)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 6/20 0.44
NR1H2 P55055 2/20 0.36
TLR9 Q9NR96 1/20 0.36
CNR1 P21554 1/20 0.35
CNR2 P34972 1/20 0.35
FAAH O00519 2/20 0.35
TSHR P16473 1/20 0.35
CES1 P23141 2/20 0.34
CDC25A P30304 1/20 0.34
NR1H3 Q13133 1/20 0.33
LTA4H P09960 1/20 0.33
PSEN1 P49768 1/20 0.32
PSEN2 P49810 1/20 0.32
APH1B Q8WW43 1/20 0.32
NCSTN Q92542 1/20 0.32
APH1A Q96BI3 1/20 0.32
PSENEN Q9NZ42 1/20 0.32
MMP2 P08253 1/20 0.32
MMP3 P08254 1/20 0.32
MMP9 P14780 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1704669 0.82 MGLL (0.51) MGLLFAAH
SCHEMBL6338124 0.80 MGLL (0.55) MGLLNR1H2TLR9FAAHTSHR
SCHEMBL29754826 0.80 MGLL (0.55) MGLLNR1H2TLR9FAAHTSHR
SCHEMBL29754607 0.77 MGLL (0.65) MGLLNR1H2TLR9FAAH
SCHEMBL6367116 0.77 CYP1A2 (0.49) CNR1CNR2LTA4H
SCHEMBL6363770 0.77 CYP1A2 (0.49) CNR1CNR2LTA4H
SCHEMBL6363523 0.77 CYP1A2 (0.49) CNR1CNR2LTA4H
SCHEMBL6366290 0.77 CYP1A2 (0.49) CNR1CNR2LTA4H
SCHEMBL6362550 0.77 CYP1A2 (0.49) CNR1CNR2LTA4H
SCHEMBL6362660 0.77 CYP1A2 (0.49) CNR1CNR2LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5932637-A FIREPROOFING LAMINATE CONSISTS OF AN EPOXY RESIN, A MALEIMIDE COMPOUND, A CURING AGENT HAVING AMINO GROUP AND A PHOSPHORUS ESTER AND A SUBSTRATE; HALOGEN-FREE AND NON-DETERIORATION SUMITOMO BAKELITE COMPANY LIMITED (JP) 1999-08-03 US disclosed