SCHEMBL1704669

SCHEMBL1704669

CCCCCCCC(C)(c1ccc(Oc2ccc(N3C(=O)C=CC3=O)cc2)cc1)c1ccc(Oc2ccc(N3C(=O)C=CC3=O)cc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 15/20 0.51
FAAH O00519 6/20 0.51
HSP90AA1 P07900 3/20 0.38
KMT2A Q03164 2/20 0.38
ALDH1A1 P00352 2/20 0.38
HPGD P15428 2/20 0.38
HTT P42858 2/20 0.38
PKM P14618 2/20 0.38
MEN1 O00255 1/20 0.38
LMNA P02545 1/20 0.38
CCR6 P51684 1/20 0.38
ATM Q13315 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
NPSR1 Q6W5P4 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
CACNA1B Q00975 1/20 0.38
APBA1 Q02410 1/20 0.38
PTGS1 P23219 3/20 0.36
PTGS2 P35354 3/20 0.36
MAPK1 P28482 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL486533 0.84 MGLL (0.57) MGLLFAAHHSP90AA1KMT2AALDH1A1
SCHEMBL8405341 0.82 MGLL (0.44) MGLLFAAH
SCHEMBL8402814 0.79 MGLL (0.83) MGLLFAAHHSP90AA1KMT2AALDH1A1
SCHEMBL15875894 0.77 MGLL (0.64) MGLLFAAHHSP90AA1KMT2AALDH1A1
SCHEMBL94891 0.77 MGLL (0.64) MGLLFAAHHSP90AA1KMT2AALDH1A1
SCHEMBL485546 0.77 MGLL (0.64) MGLLFAAHHSP90AA1KMT2AALDH1A1
SCHEMBL8852774 0.77 MGLL (0.80) MGLLFAAHHSP90AA1KMT2AALDH1A1
SCHEMBL4328660 0.76 MAPT (0.57) ALDH1A1HPGDLMNASMN1; SMN2TDP1
SCHEMBL4330091 0.76 MAPT (0.57) ALDH1A1HPGDLMNASMN1; SMN2TDP1
SCHEMBL6362740 0.76 MAPT (0.57) ALDH1A1HPGDLMNASMN1; SMN2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-6322120-A None JP disclosed
EP-3357959-B1 LOW LOSS PRE-PREGS AND LAMINATES AND COMPOSITIONS USEFUL FOR THE PREPARATION THEREOF ARLON LLC (US) 2020-11-25 EP disclosed
US-10418148-B2 Low loss pre-pregs and laminates and compositions useful for the preparation thereof ARLON LLC (US) 2019-09-17 US disclosed
EP-3357959-A1 LOW LOSS PRE-PREGS AND LAMINATES AND COMPOSITIONS USEFUL FOR THE PREPARATION THEREOF Arlon (US) 2018-08-08 EP disclosed
US-20170287589-A1 Low Loss Pre-Pregs and Laminates and Compositions Useful for the Preparation Thereof JPMORGAN CHASE BANK, N.A., AS ADMINISTRATIVE AGENT 2017-10-05 US disclosed
EP-2991995-A1 BUTADIEN2,3-DIYL LINKED DI-DOPO DERIVATIVES AS FLAME RETARDANTS Albemarle Corporation (US) 2016-03-09 EP disclosed
US-20160060281-A1 BUTADIEN2,3-DIYL LINKED DI-DOPO DERIVATIVES AS FLAME RETARDANTS ANGELL SCOTT EDWARD (US) 2016-03-03 US disclosed
WO-2015103006-A1 FLAME RETARDANT THERMOPLASTIC COMPOSITIONS ALBEMARLE CORPORATION (US) 2015-07-09 WO disclosed
WO-2014179688-A1 BUTADIEN2,3-DIYL LINKED DI-DOPO DERIVATIVES AS FLAME RETARDANTS ALBEMARLE CORPORATION (US) 2014-11-06 WO disclosed
US-20140138128-A1 Low Loss Pre-Pregs and Laminates and Compositions Useful for the Preparation Thereof ARLON (US) 2014-05-22 US disclosed
US-8658719-B2 Low loss pre-pregs and laminates and compositions useful for the preparation thereof ARLON (US) 2014-02-25 US disclosed
US-8193274-B2 Metal-clad laminates having improved peel strength and compositions useful for the preparation thereof ARLON (US) 2012-06-05 US disclosed
EP-2440610-A2 LOW LOSS PRE-PREGS AND LAMINATES AND COMPOSITIONS USEFUL FOR THE PREPARATION THEREOF Arlon (US) 2012-04-18 EP disclosed
WO-2010144615-A2 LOW LOSS PRE-PREGS AND LAMINATES AND COMPOSITIONS USEFUL FOR THE PREPARATION THEREOF ARLON (US) 2010-12-16 WO disclosed
US-20100314160-A1 LOW LOSS PRE-PREGS AND LAMINATES AND COMPOSITIONS USEFUL FOR THE PREPARATION THEREOF ARLON 2010-12-16 US disclosed
US-20090176918-A1 METAL-CLAD LAMINATES HAVING IMPROVED PEEL STRENGTH AND COMPOSITIONS USEFUL FOR THE PREPARATION THEREOF ARLON 2009-07-09 US disclosed
US-20090176106-A1 METAL-CLAD LAMINATES HAVING IMPROVED PEEL STRENGTH AND COMPOSITIONS USEFUL FOR THE PREPARATION THEREOF ARLON 2009-07-09 US disclosed
JP-H06322120-A THERMOSETTING RESIN COMPOSITION HAVING LOW DIELECTRIC DISSIPATION FACTOR SUMITOMO BAKELITE CO LTD 1994-11-22 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160060281-A1 BUTADIEN2,3-DIYL LINKED DI-DOPO DERIVATIVES AS FLAME RETARDANTS DUOX2, FFAR2, BBOX1 MGLL 2030/4885FAAH 473/4885HSP90AA1 3314/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.