Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 8/20 | 0.48 |
| ▸ | MAOA | P21397 | 3/20 | 0.48 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | FNTA | P49354 | 1/20 | 0.43 |
| ▸ | FNTB | P49356 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8405497 | 0.90 | MEN1 (0.47) | CCR5MAOBMAOAAPPNR4A2 | |
| SCHEMBL8408576 | 0.84 | LMNA (0.54) | MAOBNR4A2MAPT | |
| SCHEMBL8409129 | 0.83 | APP (0.53) | MAOBMAOAAPPFNTAFNTB | |
| SCHEMBL11298129 | 0.81 | TTR (0.47) | MAOBMAOATTRMAPTTHRA | |
| SCHEMBL8408730 | 0.77 | MAPT (0.51) | CCR5MAOBMAOAAPPNR4A2 | |
| SCHEMBL8405445 | 0.76 | FFAR1 (0.49) | MAOBNR4A2THRATHRB | |
| SCHEMBL4701129 | 0.74 | MAOB (0.63) | MAOBMAOAAPPNR4A2 | |
| SCHEMBL8405973 | 0.74 | PPARG (0.47) | MAOBNR4A2 | |
| SCHEMBL8405685 | 0.73 | THRA (0.60) | MAOBMAOAAPPNR4A2FNTA | |
| SCHEMBL6725152 | 0.72 | MRGPRX4 (0.55) | CCR5MAOBMAOANR4A2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5872137-A | AROMATIC OXY DIHALOPRENE COMPOUNDS INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-02-16 | — | — | US | disclosed |
| EP-0722430-B1 | DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL CO (JP) | 1998-10-21 | — | — | EP | disclosed |