Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.47 |
| ▸ | CBR1 | P16152 | 1/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10943307 | 0.87 | STK39 (0.52) | TTRHPGDLMNANR1I2PGR | |
| SCHEMBL8405686 | 0.81 | CCR5 (0.48) | TTRMAPTTHRATHRBMAPK1 | |
| SCHEMBL28849634 | 0.80 | THRA (0.60) | LMNAHSP90AA1TSHRHSD17B10ALDH1A1 | |
| SCHEMBL11296576 | 0.77 | TSHR (0.43) | HPGDMAPTTSHRALDH1A1MAOA | |
| SCHEMBL8913702 | 0.73 | TTR (0.72) | TTRHPGDLMNANR1I2PGR | |
| SCHEMBL8945699 | 0.72 | MAOA (0.59) | HPGDLMNAMAPTTSHRALDH1A1 | |
| Soneclosan SCHEMBL29359126 | 0.72 | TTR (0.66) | TTRHPGDLMNANR1I2PGR | |
| Soneclosan SCHEMBL465591 | 0.72 | TTR (0.66) | TTRHPGDLMNANR1I2PGR | |
| SCHEMBL5543172 | 0.72 | CYP2C9 (0.41) | HPGDLMNAMAPTTSHRALDH1A1 | |
| SCHEMBL9683631 | 0.72 | MAOA (0.59) | HPGDMAPTTSHRALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0012108-B1 | PROCESS FOR THE PREPARATION OF 4,5-DICHLORO-2-(4-CHLOROPHENOXY)-PHENOL AND OF 4,5-DICHLORO-2-(4-CHLOROPHENOXY)-ANISOL | CIBA-GEIGY AG (CH) | 1982-07-28 | — | — | EP | disclosed |
| US-4284828-A | Process for the manufacture of 4,5-dichloro-2-(4-chlorophenoxy)phenol | CIBA-GEIGY CORPORATION (US) | 1981-08-18 | — | — | US | disclosed |
| EP-0012108-A1 | Process for the preparation of 4,5-dichloro-2-(4-chlorophenoxy)-phenol and of 4,5-dichloro-2-(4-chlorophenoxy)-anisol | CIBA-GEIGY AG (CH) | 1980-06-11 | — | — | EP | disclosed |