SCHEMBL8406136

SCHEMBL8406136

c1ccc(-c2cccc(-c3c4ccccc4c(-c4cccc(-c5ccccc5)c4)c4c(N(c5ccccc5)c5ccc(N(c6ccccc6)c6ccccc6)cc5)cccc34)c2)cc1

nearest known ligand 0.33

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
MAPT P10636 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
KMO O15229 1/20 0.33
MGLL Q99685 1/20 0.31
GP6 Q9HCN6 1/20 0.30
MAOA P21397 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8406139 0.91 ALDH1A1 (0.35) KDM4EALDH1A1CYP1A2CYP3A4CYP2D6
SCHEMBL8406124 0.91 ALDH1A1 (0.37) KDM4EALDH1A1CYP1A2CYP3A4CYP2D6
SCHEMBL27998248 0.88 ACHE (0.35) KDM4EALDH1A1CYP1A2CYP3A4CYP2D6
SCHEMBL10112342 0.87 PTGDR2 (0.38) KDM4EALDH1A1CYP1A2CYP3A4CYP2D6
SCHEMBL8406190 0.86 KDM4E (0.39) KDM4EL3MBTL1
SCHEMBL9971797 0.86 ALDH1A1 (0.41) KDM4EALDH1A1CYP1A2CYP3A4CYP2D6
SCHEMBL10112363 0.85
SCHEMBL10112376 0.85 KMO (0.45) KDM4EALDH1A1KMO
SCHEMBL10112434 0.85 NPC1 (0.42) KDM4EALDH1A1CYP1A2MAPT
SCHEMBL10112405 0.85 HTR1A (0.33) KDM4ETDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160197278-A1 Anthracene Derivative, and Light-Emitting Element, Light-Emitting Device, Electronic Device Using Anthracene Derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-07-07 US disclosed
US-20160197278-A1 Anthracene Derivative, and Light-Emitting Element, Light-Emitting Device, Electronic Device Using Anthracene Derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-07-07 US disclosed
US-9287511-B2 Anthracene derivative, and light-emitting element, light-emitting device, electronic device using anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-03-15 US disclosed
EP-2084123-B1 ANTHRACENE DERIVATIVE, AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE USING ANTHRACENE DERIVATIVE SEMICONDUCTOR ENERGY LAB (JP) 2014-08-27 EP disclosed
US-20130306941-A1 Anthracene Derivative, and Light-Emitting Element, Light-Emitting Device, Electronic Device Using Anthracene Derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-11-21 US disclosed
US-8431252-B2 Anthracene derivative, and light-emitting element, light-emitting device, electronic device using anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-04-30 US disclosed
US-8431252-B2 Anthracene derivative, and light-emitting element, light-emitting device, electronic device using anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2013-04-30 US disclosed
US-20120126215-A1 Anthracene Derivative, and Light-Emitting Element, Light-Emitting Device, Electronic Device Using Anthracene Derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-05-24 US disclosed
US-20120126215-A1 Anthracene Derivative, and Light-Emitting Element, Light-Emitting Device, Electronic Device Using Anthracene Derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-05-24 US disclosed
US-8106392-B2 Anthracene derivative, and light-emitting element, light-emitting device, electronic device using anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-01-31 US disclosed
US-8106392-B2 Anthracene derivative, and light-emitting element, light-emitting device, electronic device using anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-01-31 US disclosed
US-20110062428-A1 Anthracene Derivative, and Light-Emitting Element, Light-Emitting Device, Electronic Device Using Anthracene Derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2011-03-17 US disclosed
US-20110062428-A1 Anthracene Derivative, and Light-Emitting Element, Light-Emitting Device, Electronic Device Using Anthracene Derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2011-03-17 US disclosed
US-7842945-B2 Anthracene derivative, and light-emitting element, light-emitting device, electronic device using anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-11-30 US disclosed
US-7842945-B2 Anthracene derivative, and light-emitting element, light-emitting device, electronic device using anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-11-30 US disclosed
US-20080017853-A1 Anthracene derivative, and light-emitting element, light-emitting device, electronic device using anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-01-24 US disclosed
US-20080017853-A1 Anthracene derivative, and light-emitting element, light-emitting device, electronic device using anthracene derivative SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2008-01-24 US disclosed
WO-2007125934-A1 ANTHRACENE DERIVATIVE, AND LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE USING ANTHRACENE DERIVATIVE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2007-11-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080017853-A1 Anthracene derivative, and light-emitting element, light-emitting device, electronic device using anthracene derivative XPOT, XPO1, XPO7 KDM4E 3837/4885ALDH1A1 45/4885CYP1A2 27/4885
US-20160197278-A1 Anthracene Derivative, and Light-Emitting Element, Light-Emitting Device, Electronic Device Using Anthracene Derivative XPOT, XPO1, XPO7 KDM4E 3837/4885ALDH1A1 45/4885CYP1A2 27/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.