Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8409813 | 0.87 | LMNA (0.37) | TSHRMAPT | |
| SCHEMBL9893490 | 0.78 | ALDH1A1 (0.45) | TSHRALDH1A1TDP1CYP3A4CA2 | |
| SCHEMBL8123553 | 0.70 | CA2 (0.39) | TSHRALDH1A1TDP1CYP3A4CA2 | |
| SCHEMBL16735918 | 0.69 | ELANE (0.41) | — | |
| SCHEMBL1594490 | 0.69 | ALDH1A1 (0.33) | TSHRALDH1A1TDP1CYP3A4CA2 | |
| SCHEMBL16736010 | 0.67 | MMP2 (0.37) | — | |
| SCHEMBL11131328 | 0.66 | CA2 (0.41) | TSHRALDH1A1TDP1CYP3A4CA2 | |
| SCHEMBL387001 | 0.63 | — | — | |
| SCHEMBL3884493 | 0.63 | ALDH1A1 (0.68) | TSHRALDH1A1TDP1CYP3A4CA2 | |
| SCHEMBL2422013 | 0.63 | ALDH1A1 (0.45) | TSHRALDH1A1TDP1CYP3A4CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0663206-B1 | Naphthalenmethylenemalonic diesters, and UV absorbers and cosmetic compositions containing the diesters | KAO CORP (JP) | 1999-07-14 | — | — | EP | disclosed |
| US-5508025-A | SUNSCREEN AGENTS | KAO CORPORATION (JP) | 1996-04-16 | — | — | US | disclosed |
| EP-0663206-A1 | Naphthalenmethylenemalonic diesters, and UV absorbers and cosmetic compositions containing the diesters | Kao Corporation (JP) | 1995-07-19 | — | — | EP | disclosed |