Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 3/20 | 0.37 |
| ▸ | HTR1A | P08908 | 4/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 3/20 | 0.33 |
| ▸ | HTR6 | P50406 | 2/20 | 0.33 |
| ▸ | HTR5A | P47898 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11034435 | 0.73 | HTR2A (0.42) | MEN1KMT2AHTR2AOPRM1HTR2B | |
| SCHEMBL8588165 | 0.70 | HTR2A (0.39) | HTR2ASLC6A2SLC6A4OPRM1HTR2B | |
| SCHEMBL4432181 | 0.70 | HTR2A (0.39) | MEN1KMT2AHTR2AOPRM1HTR3A | |
| SCHEMBL5915111 | 0.68 | OPRM1 (0.40) | HTR2AOPRM1 | |
| SCHEMBL29448034 | 0.67 | ADRB1 (0.62) | HTR2AHTR1ASLC6A2SLC6A4HTR7 | |
| SCHEMBL2414711 | 0.67 | ADRB1 (0.62) | HTR2AHTR1ASLC6A2SLC6A4HTR7 | |
| SCHEMBL234734 | 0.67 | ADRB1 (0.62) | HTR2AHTR1ASLC6A2SLC6A4HTR7 | |
| SCHEMBL1442618 | 0.66 | SIGMAR1 (0.47) | MEN1KMT2AHTR2AHTR1ASLC6A2 | |
| SCHEMBL8223305 | 0.66 | FAAH (0.38) | MEN1KMT2AHTR2AOPRM1OPRL1 | |
| Hydrochloric Acid SCHEMBL1239646 | 0.65 | ADRB1 (0.60) | HTR2AHTR1ASLC6A2SLC6A4HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919784-A | ANXIETY, DEPRESSION | ADIR ET COMPAGNIE (FR) | 1999-07-06 | — | — | US | disclosed |