SCHEMBL8406580

SCHEMBL8406580

CCCCCCCCSCCSc1nc2nc(C)cc(O)n2n1

nearest known ligand 0.49

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.49
HTT P42858 2/20 0.49
CYP2C19 P33261 2/20 0.49
CYP3A4 P08684 1/20 0.49
CYP2D6 P10635 1/20 0.49
MAPT P10636 1/20 0.49
CYP2C9 P11712 1/20 0.49
KDM1A O60341 3/20 0.49
KDM4E B2RXH2 1/20 0.47
GAA P10253 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
HPGD P15428 3/20 0.43
LMNA P02545 1/20 0.43
ALDH1A1 P00352 3/20 0.43
ABCB1 P08183 1/20 0.43
ALOX15 P16050 1/20 0.42
RECQL P46063 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8403913 1.00 CYP1A2 (0.49) CYP1A2HTTCYP2C19CYP3A4CYP2D6
SCHEMBL8406579 1.00 CYP1A2 (0.49) CYP1A2HTTCYP2C19CYP3A4CYP2D6
SCHEMBL8406523 0.94 CYP1A2 (0.50) CYP1A2HTTCYP2C19CYP3A4CYP2D6
SCHEMBL13996431 0.72 ALDH1A1 (0.59) CYP1A2MAPTKDM1AKDM4EGAA
SCHEMBL10623008 0.72 SMN1; SMN2 (0.57) CYP1A2KDM1AKDM4EGAASMN1; SMN2
SCHEMBL8520132 0.72 KDM1A (0.67) CYP1A2CYP2C19CYP3A4KDM1AKDM4E
SCHEMBL2315537 0.72 ALDH1A1 (0.57) CYP1A2CYP2C19CYP3A4KDM1AKDM4E
SCHEMBL5685870 0.68 HTT (0.41) CYP1A2HTTCYP2C19CYP3A4CYP2D6
SCHEMBL4613719 0.66 L3MBTL1 (0.46) HTTGAASMN1; SMN2HPGDLMNA
SCHEMBL7100505 0.66 RECQL (0.54) CYP1A2HTTKDM4ESMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0574331-B1 Tone control of photographic images EASTMAN KODAK CO (US) 1999-07-28 EP disclosed
EP-0573373-B1 Tone control of photographic silver images EASTMAN KODAK CO (US) 1999-07-14 EP disclosed
EP-0575262-B1 Radiographic elements with improved covering power EASTMAN KODAK CO (US) 1999-07-07 EP disclosed
US-5314790-A Tetrazoles or triazoles EASTMAN KODAK COMPANY (US) 1994-05-24 US disclosed
US-5292627-A Azole to modify tone EASTMAN KODAK COMPANY (US) 1994-03-08 US disclosed
US-5292631-A Radiographic elements with improved covering power EASTMAN KODAK COMPANY (US) 1994-03-08 US disclosed
EP-0575262-A2 Radiographic elements with improved covering power EASTMAN KODAK COMPANY (US) 1993-12-22 EP disclosed
EP-0574331-A2 Tone control of photographic images EASTMAN KODAK COMPANY (US) 1993-12-15 EP disclosed
EP-0573373-A2 Tone control of photographic silver images EASTMAN KODAK COMPANY (US) 1993-12-08 EP disclosed