Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 18/20 | 0.58 |
| ▸ | PGR | P06401 | 11/20 | 0.58 |
| ▸ | AR | P10275 | 9/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8408966 | 1.00 | NR3C1 (0.58) | NR3C1PGRARCYP3A4CYP2C8 | |
| SCHEMBL8653388 | 0.82 | NR3C1 (0.61) | NR3C1PGRARCYP3A4CYP2C8 | |
| SCHEMBL10944303 | 0.81 | NR3C1 (0.45) | NR3C1PGRARCYP3A4CYP2C8 | |
| SCHEMBL8408961 | 0.80 | NR3C1 (0.57) | NR3C1PGRARCYP2C8 | |
| SCHEMBL8621595 | 0.79 | NR3C1 (0.60) | NR3C1PGRARCYP3A4CYP2C8 | |
| SCHEMBL21729781 | 0.79 | NR3C1 (0.68) | NR3C1PGRARCYP3A4CYP2C8 | |
| SCHEMBL19042656 | 0.79 | NR3C1 (0.68) | NR3C1PGRARCYP3A4CYP2C8 | |
| SCHEMBL24476242 | 0.78 | PGR (0.53) | NR3C1PGRARCYP3A4 | |
| SCHEMBL9019810 | 0.77 | PGR (0.65) | NR3C1PGRARCYP3A4CYP2C8 | |
| SCHEMBL9019846 | 0.77 | NR3C1 (0.83) | NR3C1PGRARCYP3A4CYP2C8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0565553-B1 | 6,7-MODIFIED 11$g(b)-ARYL-4-ESTRENES | SCHERING AG (DE) | 1999-07-21 | — | — | EP | claimed |
| US-5843931-A | 6,7-modified 11β-aryl-4-oestrenes | SHERING AKTIENGESELLSCHAFT (DE) | 1998-12-01 | — | — | US | disclosed |