Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 9/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 3/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8407140 | 0.86 | MLYCD (0.48) | MLYCDALDH1A1HPGDPGRAR | |
| SCHEMBL8409270 | 0.76 | MLYCD (0.44) | MLYCDALDH1A1PGRARMAOA | |
| SCHEMBL28308819 | 0.75 | SLC16A3 (0.42) | ALDH1A1HPGDPGRARNOS2 | |
| SCHEMBL18997806 | 0.74 | MLYCD (0.62) | MLYCDALDH1A1HPGDADRB2TSHR | |
| SCHEMBL11453144 | 0.70 | MLYCD (0.53) | MLYCDALDH1A1ADRB2 | |
| SCHEMBL3048940 | 0.69 | AR (0.44) | PGRARNOS2MAOAMAOB | |
| SCHEMBL6843869 | 0.68 | MLYCD (1.00) | MLYCD | |
| SCHEMBL4896904 | 0.68 | MAOA (0.38) | PGRARNOS2MAOAMAOB | |
| SCHEMBL4896895 | 0.68 | MAOA (0.38) | PGRARNOS2MAOAMAOB | |
| SCHEMBL4219142 | 0.68 | PGR (0.40) | MLYCDALDH1A1PGRARMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5994362-A | ADMINISTERING FINASTERIDE AND CASODEX | MERCK & CO., INC. (US) | 1999-11-30 | — | — | US | disclosed |
| EP-0514056-A2 | Use of estrogens or antiandrogens for reversal of male sexual phenotype in poultry | MERCK & CO. INC. (US) | 1992-11-19 | — | — | EP | disclosed |
| WO-1992016233-A1 | PHARMACEUTICAL COMBINATION FOR THE TREATMENT OF PROSTATIC CANCER CONTAINING A 5 ALPHA REDUCTASE INHIBITOR AND AN ANTIANDROGEN | MERCK & CO., INC. (US) | 1992-10-01 | — | — | WO | disclosed |
| EP-0002309-B1 | ACYLANILIDES, PROCESS FOR THEIR MANUFACTURE AND PHARMACEUTICAL AND VETERINARY COMPOSITIONS CONTAINING THEM | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-12-01 | — | — | EP | disclosed |
| US-4282218-A | ANTIANDROGENS | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1981-08-04 | — | — | US | disclosed |
| US-4239776-A | Anti-androgenic amides | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1980-12-16 | — | — | US | disclosed |
| EP-0002309-A2 | Acylanilides, process for their manufacture and pharmaceutical and veterinary compositions containing them | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1979-06-13 | — | — | EP | disclosed |