Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 6/20 | 0.43 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALPG | P10696 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | LPL | P06858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29103227 | 0.97 | ACHE (0.42) | ACHEBCHELMNATSHRALOX12 | |
| Hydrochloric Acid SCHEMBL29103228 | 0.97 | ACHE (0.42) | ACHEBCHELMNATSHRALOX12 | |
| Iodide SCHEMBL10358237 | 0.97 | ACHE (0.42) | ACHEBCHELMNATSHRALOX12 | |
| Hydrochloric Acid SCHEMBL4727803 | 0.97 | ACHE (0.42) | ACHEBCHELMNATSHRALOX12 | |
| SCHEMBL28799098 | 0.91 | ACHE (0.39) | ACHEBCHELMNATSHRALOX12 | |
| Hydrochloric Acid SCHEMBL29103122 | 0.91 | RAB9A (0.43) | ACHEBCHELMNATSHRALOX12 | |
| SCHEMBL776579 | 0.86 | NPC1 (0.37) | ACHEALDH1A1KDM4EHTTRAB9A | |
| Acetic Acid SCHEMBL29025324 | 0.85 | CES2 (0.39) | ACHEBCHELMNATDP1ALDH1A1 | |
| SCHEMBL23058911 | 0.81 | SLC22A2 (0.48) | ACHEBCHELMNATSHRALOX12 | |
| SCHEMBL5301154 | 0.79 | ACHE (0.50) | ACHEBCHELMNATSHRALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 290 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220193076-A1 | METHODS OF TREATING BREAST CANCER WITH TUCATINIB | SEAGEN INC (US) | 2022-06-23 | — | — | US | claimed |
| EP-3917533-A1 | METHODS OF TREATING BREAST CANCER WITH TUCATINIB | Seagen Inc. (US) | 2021-12-08 | — | — | EP | claimed |
| CN-113613656-A | Method of treating breast cancer with ceratinib | 西根股份有限公司 | 2021-11-05 | — | — | CN | claimed |
| WO-2020159822-A1 | METHODS OF TREATING BREAST CANCER WITH TUCATINIB | SEATTLE GENETICS, INC. (US) | 2020-08-06 | — | — | WO | claimed |
| CN-104974227-B | The amphiphilic film targeting alpha-helix polypeptide of cation and its application | 中国科学院苏州纳米技术与纳米仿生研究所 | 2019-04-23 | — | — | CN | claimed |
| CN-107529563-A | A kind of chemical copper activator and preparation method | 苏州天承化工有限公司 | 2018-01-02 | — | — | CN | claimed |
| CN-107129519-A | Polypeptide fluorescence cyclization method and cyclized polypeptide based on metal iridium complex | 中国科学院苏州纳米技术与纳米仿生研究所 | 2017-09-05 | — | — | CN | claimed |
| CN-104974227-A | Cation amphiphilic membrane targeted alpha-helix polypeptides and application thereof | SUZHOU INST NANO TECH & NANO B | 2015-10-14 | — | — | CN | claimed |
| US-20080132447-A1 | Method of Screening for a Carnitine Transporter Agonist or Antagonist and it Uses | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2008-06-05 | — | — | US | claimed |
| EP-1781817-A2 | METHOD OF SCREENING FOR A CARNITINE TRANSPORTER AGONIST OR ANTAGONIST AND ITS USES | Sanofi-Aventis Deutschland GmbH (DE) | 2007-05-09 | — | — | EP | claimed |
| WO-2006018259-A2 | METHOD OF SCREENING FOR A CARNITINE TRANSPORTER AGONIST OR ANTAGONIST AND ITS USES | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2006-02-23 | — | — | WO | claimed |
| EP-1627922-A1 | Method of screening for a carnitine transporter agonist or antagonist and its uses | Sanofi-Aventis Deutschland GmbH (DE) | 2006-02-22 | — | — | EP | claimed |
| WO-2023093905-A1 | AADC/GDNF POLYNUCLEOTIDE, AND USE THEREOF IN TREATING PARKINSON'S DISEASE | 上海瑞宏迪医药有限公司 | 2023-06-01 | — | — | WO | disclosed |
| US-20230130980-A1 | HIGH PENETRATION PRODRUG COMPOSITIONS OF ANTIMICROBIALS AND ANTIMICROBIAL-RELATED COMPOUNDS | TECHFIELDS PHARMA CO., LTD. (CN) | 2023-04-27 | — | — | US | disclosed |
| US-20220193076-A1 | METHODS OF TREATING BREAST CANCER WITH TUCATINIB | SEAGEN INC (US) | 2022-06-23 | — | — | US | disclosed |
| EP-3917533-A1 | METHODS OF TREATING BREAST CANCER WITH TUCATINIB | Seagen Inc. (US) | 2021-12-08 | — | — | EP | disclosed |
| WO-2001026641-A2 | MORPHOLINOL DERIVATIVES FOR THE TREATMENT OF OBESITY | GLAXO GROUP LIMITED (GB) | 2001-04-19 | — | — | WO | disclosed |
| US-5589513-A | TREATMENT OF NEURODEGENERATIVE DISEASES; MONOAMINE OXIDASE INHIBITOR AND UPTAKE INHIBITOR | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1996-12-31 | — | — | US | disclosed |
| EP-0617615-A1 | PHARMACEUTICAL COMPOSITION AND PROCESS FOR THE PREPARATION THEREOF | CHINOIN Gyogyszer és Vegyészeti Termékek Gyára RT. (HU) | 1994-10-05 | — | — | EP | disclosed |
| WO-1993012775-A1 | PHARMACEUTICAL COMPOSITION AND PROCESS FOR THE PREPARATION THEREOF | CHINOIN GYÓGYSZER- ÉS VEGYÉSZETI TERMÉKEK GYÁRA RT. (HU) | 1993-07-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220193076-A1 | METHODS OF TREATING BREAST CANCER WITH TUCATINIB | BRCA1, TTBK2, TTBK1 | ACHE 2350/4885BCHE 2461/4885LMNA 2996/4885 |
| US-20230130980-A1 | HIGH PENETRATION PRODRUG COMPOSITIONS OF ANTIMICROBIALS AND ANTIMICROBIAL-RELATED COMPOUNDS | SLC7A1, VIP, HPGDS | ACHE 2976/4885BCHE 482/4885LMNA 4309/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.