Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CDC25B | P30305 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | PTPRC | P08575 | 2/20 | 0.37 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8407442 | 0.92 | CDC25B (0.46) | KDM4ECDC25BMAPTKMT2APTK2B | |
| SCHEMBL8533482 | 0.89 | ALDH1A1 (0.39) | KDM4ELMNAALDH1A1MAPTKMT2A | |
| SCHEMBL11545967 | 0.84 | LMNA (0.42) | LMNAALDH1A1MAPTKMT2APKM | |
| SCHEMBL576239 | 0.84 | KMT2A (0.39) | LMNAALDH1A1MAPTKMT2AESR1 | |
| SCHEMBL577321 | 0.83 | LMNA (0.44) | LMNAALDH1A1MAPTKMT2ATDP1 | |
| Ethylene Glycol SCHEMBL6480858 | 0.81 | KDM4E (0.38) | KDM4ECDC25BMAPTKMT2APKM | |
| SCHEMBL576888 | 0.81 | P2RX1 (0.43) | KDM4ELMNAALDH1A1MAPTKMT2A | |
| SCHEMBL10716723 | 0.80 | CES2 (0.48) | LMNAALDH1A1MAPTKMT2ATDP1 | |
| SCHEMBL27901682 | 0.79 | CDC25B (0.52) | KDM4ECDC25BALDH1A1MAPTKMT2A | |
| SCHEMBL271358 | 0.79 | CDC25B (0.52) | KDM4ECDC25BALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891970-A | AMIDATION WITH 2-SULFOBENZOIC ANHYDRIDE | NATIONAL SCIENCE COUNCIL OF REPUBLIC OF CHINA (TW) | 1999-04-06 | — | — | US | disclosed |
| US-5462991-A | Pthalein-type | ROBOTTI KARLA M (US) | 1995-10-31 | — | — | US | disclosed |
| US-5384411-A | Phthalien dyes | HEWLETT-PACKARD COMPANY (US) | 1995-01-24 | — | — | US | disclosed |
| EP-0519198-A2 | Immobilization of PH-sensitive dyes to solid supports | Hewlett-Packard Company (US) | 1992-12-23 | — | — | EP | disclosed |
| US-3996202-A | Process for the preparation of sulfonate group containing aromatic polyamides | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-12-07 | — | — | US | disclosed |