SCHEMBL8533482

SCHEMBL8533482

O=C(Cl)c1ccc(C(=O)OC(=O)c2ccccc2)c(S(=O)(=O)O)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.39
MAPT P10636 3/20 0.39
LMNA P02545 2/20 0.39
KMT2A Q03164 2/20 0.39
F2 P00734 1/20 0.36
ESR1 P03372 1/20 0.35
ESR2 Q92731 1/20 0.35
TSHR P16473 4/20 0.34
TDP1 Q9NUW8 3/20 0.33
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
HSD17B10 Q99714 1/20 0.33
CA12 O43570 1/20 0.33
CA9 Q16790 1/20 0.33
KDM4E B2RXH2 2/20 0.33
CA7 P43166 1/20 0.32
CA13 Q8N1Q1 1/20 0.32
POLB P06746 1/20 0.32
PARP10 Q53GL7 1/20 0.32
MEN1 O00255 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8533484 0.91 KDM4E (0.33) ALDH1A1MAPTLMNAKMT2ATSHR
SCHEMBL8407447 0.89 KDM4E (0.44) ALDH1A1MAPTLMNAKMT2AF2
SCHEMBL11545967 0.82 LMNA (0.42) ALDH1A1MAPTLMNAKMT2AF2
SCHEMBL576239 0.82 KMT2A (0.39) ALDH1A1MAPTLMNAKMT2AF2
SCHEMBL8407442 0.81 CDC25B (0.46) MAPTKMT2ATSHRTDP1CA1
SCHEMBL577321 0.81 LMNA (0.44) ALDH1A1MAPTLMNAKMT2AF2
SCHEMBL890520 0.78 CDC25B (0.34) ALDH1A1MAPTLMNAKMT2ATSHR
SCHEMBL576888 0.78 P2RX1 (0.43) ALDH1A1MAPTLMNAKMT2ATDP1
SCHEMBL10716723 0.77 CES2 (0.48) ALDH1A1MAPTLMNAKMT2ATDP1
SCHEMBL7932106 0.77 CDC25B (0.33) ALDH1A1MAPTLMNAKMT2ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0517203-B1 Acid-dye resistant polyamide products and process for preparation BASF CORP (US) 1998-02-04 EP claimed
US-5562871-A CHEMICALLY BLOCKING A PORTION OF AMINO END GROUPS IN SULPHONATED POLYMER BASF CORPORATION (US) 1996-10-08 US claimed
US-5560973-A SULFONATED POLYMER BASF CORPORATION (US) 1996-10-01 US claimed
US-5548037-A INCLUDING SULFONATED GROUPS AND AN AMINE END BLOCKER BASF CORPORATION (US) 1996-08-20 US claimed
US-5545363-A SULFONATING, PIGMENTING, BLOCKING SULFONATED POLYAMIDE, FINALLY MELT SPINNING BASF CORPORATION (US) 1996-08-13 US claimed
US-5340886-A Acylation with a sulfonate compound, coloring, blocking and amidation with an alkyl anhydride, alkylaryl anhydride or a lactones BASF CORPORATION (US) 1994-08-23 US claimed
EP-0517203-A2 Acid-dye resistant polyamide products and process for preparation BASF CORPORATION (US) 1992-12-09 EP claimed
EP-0517203-B1 Acid-dye resistant polyamide products and process for preparation BASF CORP (US) 1998-02-04 EP disclosed
US-5562871-A CHEMICALLY BLOCKING A PORTION OF AMINO END GROUPS IN SULPHONATED POLYMER BASF CORPORATION (US) 1996-10-08 US disclosed
US-5560973-A SULFONATED POLYMER BASF CORPORATION (US) 1996-10-01 US disclosed
US-5548037-A INCLUDING SULFONATED GROUPS AND AN AMINE END BLOCKER BASF CORPORATION (US) 1996-08-20 US disclosed
US-5545363-A SULFONATING, PIGMENTING, BLOCKING SULFONATED POLYAMIDE, FINALLY MELT SPINNING BASF CORPORATION (US) 1996-08-13 US disclosed
US-5340886-A Acylation with a sulfonate compound, coloring, blocking and amidation with an alkyl anhydride, alkylaryl anhydride or a lactones BASF CORPORATION (US) 1994-08-23 US disclosed
EP-0517203-A2 Acid-dye resistant polyamide products and process for preparation BASF CORPORATION (US) 1992-12-09 EP disclosed
US-3996202-A Process for the preparation of sulfonate group containing aromatic polyamides HOECHST AKTIENGESELLSCHAFT (DT) 1976-12-07 US disclosed
US-3996202-A Process for the preparation of sulfonate group containing aromatic polyamides HOECHST AKTIENGESELLSCHAFT (DT) 1976-12-07 US disclosed