Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 5/20 | 0.47 |
| ▸ | KDM1A | O60341 | 6/20 | 0.45 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | NAT1 | P18440 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8076757 | 0.68 | PTGS2 (0.59) | — | |
| SCHEMBL3791521 | 0.68 | PGR (0.81) | PGRCYP1A2CYP2C19 | |
| SCHEMBL8407587 | 0.68 | CA2 (0.42) | CYP1A2CYP2C19 | |
| SCHEMBL8404844 | 0.66 | ALDH1A1 (0.49) | CYP2C9CYP2C19 | |
| SCHEMBL3756876 | 0.65 | PGR (1.00) | PGR | |
| SCHEMBL25351370 | 0.63 | PGR (0.47) | PGRKDM1AMAOAERBB2HSP90AA1 | |
| SCHEMBL8505677 | 0.63 | ALDH1A1 (0.41) | ERBB2HSP90AA1HSP90AB1CYP2C9 | |
| SCHEMBL8502313 | 0.63 | ALDH1A1 (0.49) | PGRERBB2HSP90AA1HSP90AB1CYP2C9 | |
| SCHEMBL8502466 | 0.63 | CYP2C9 (0.53) | CYP2C9CYP2C19 | |
| SCHEMBL25351000 | 0.63 | NAT1 (0.48) | PGRKDM1AMAOANAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5859036-A | ANTIINFLAMMATORY AGENTS, ANALGESICS | LABORATORIES UPSA (FR) | 1999-01-12 | — | — | US | disclosed |