Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 11/20 | 0.61 |
| ▸ | CTSS | P25774 | 3/20 | 0.54 |
| ▸ | CTSL | P07711 | 2/20 | 0.54 |
| ▸ | CTSB | P07858 | 2/20 | 0.54 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.53 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.50 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.50 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27450496 | 0.89 | CTSK (0.57) | CTSKCTSSCTSLCTSBLARS1 | |
| SCHEMBL6984142 | 0.89 | CTSK (0.57) | CTSKCTSSCTSLCTSBLARS1 | |
| SCHEMBL11072087 | 0.85 | CTSK (0.60) | CTSKCTSSCTSLCTSBSLC1A3 | |
| SCHEMBL6703437 | 0.83 | CTSK (0.54) | CTSKCTSSCTSLCTSBSLC1A3 | |
| SCHEMBL10414351 | 0.83 | SLC1A3 (0.57) | CTSKSLC1A3SLC1A1 | |
| SCHEMBL11061792 | 0.82 | TGM2 (0.56) | CTSKSLC1A3SLC1A1 | |
| SCHEMBL11060790 | 0.82 | TGM2 (0.56) | CTSKSLC1A3SLC1A1 | |
| SCHEMBL14493054 | 0.82 | CTSK (0.53) | CTSKCTSSCTSLCTSBLARS1 | |
| SCHEMBL7113329 | 0.82 | CTSK (0.58) | CTSKCTSSCTSLCTSB | |
| SCHEMBL353695 | 0.82 | ALDH1A1 (0.53) | CTSKCTSSCTSLCTSBSLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5998470-A | Protease inhibitors | SMITHKLINE BEECHAM CORPORATION (US) | 1999-12-07 | — | — | US | disclosed |