SCHEMBL8408671

SCHEMBL8408671

OC1CC=C(c2ccccc2)C1

nearest known ligand 0.38

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SLC18A3 Q16572 2/20 0.38
SIGMAR1 Q99720 1/20 0.36
HTR2C P28335 1/20 0.35
MAT2A P31153 1/20 0.35
DRD2 P14416 1/20 0.34
DRD4 P21917 1/20 0.34
DRD3 P35462 1/20 0.34
ALDH1A1 P00352 2/20 0.33
GAA P10253 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14336997 0.81 MAT2A (0.45) SLC18A3SIGMAR1HTR2CMAT2AALDH1A1
SCHEMBL28492138 0.75 SIGMAR1 (0.39) SLC18A3SIGMAR1HTR2CMAT2A
SCHEMBL4917795 0.74 SIGMAR1 (0.36) SLC18A3SIGMAR1HTR2CDRD2DRD4
SCHEMBL7809957 0.74 NPC1 (0.43) ALDH1A1GAA
SCHEMBL11328157 0.72 GAA (0.41) SLC18A3SIGMAR1HTR2CALDH1A1GAA
Biphenyl SCHEMBL28893342 0.68 ALDH1A1 (0.56) ALDH1A1
SCHEMBL23857833 0.67 ALDH1A1 (0.40) SLC18A3ALDH1A1
SCHEMBL6296791 0.67 CFTR (0.42) ALDH1A1
SCHEMBL893700 0.65
Biphenyl SCHEMBL8027156 0.64 ALDH1A1 (0.50) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5925676-A INSECICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-07-20 US disclosed
CN-1176960-A Novel ester compounds, pesticidal compositions containing same and intermediates for synthesis thereof SUMITOMO CHEMICAL CO (JP) 1998-03-25 CN disclosed
EP-0829467-A1 Novel ester compounds, pesticidal compositions containing the same and intermediates for synthesis thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-03-18 EP disclosed