Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.62 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.62 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10817102 | 0.82 | MTNR1A (0.44) | MTNR1AMTNR1BMEN1KMT2ACYP3A4 | |
| SCHEMBL23261872 | 0.80 | MEN1 (0.45) | MTNR1AMTNR1BMEN1KMT2ACYP3A4 | |
| SCHEMBL6075588 | 0.80 | MTNR1A (0.72) | MTNR1AMTNR1BHTR1ACA1CA2 | |
| SCHEMBL6077100 | 0.79 | MTNR1A (0.70) | MTNR1AMTNR1BHTR1ACA1CA2 | |
| SCHEMBL6075567 | 0.79 | MTNR1A (0.70) | MTNR1AMTNR1BHTR1ACA1CA2 | |
| SCHEMBL6076480 | 0.79 | MTNR1A (0.70) | MTNR1AMTNR1BHTR1ACA1CA2 | |
| SCHEMBL8406961 | 0.79 | MTNR1A (0.57) | MTNR1AMTNR1BCA1CA2CA12 | |
| SCHEMBL8409830 | 0.78 | MTNR1A (0.69) | MTNR1AMTNR1BHTR1ACA1CA2 | |
| SCHEMBL8409987 | 0.77 | MTNR1A (1.00) | MTNR1AMTNR1B | |
| SCHEMBL10992208 | 0.77 | DRD2 (0.42) | MEN1KMT2ACYP3A4LMNACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0737670-B1 | Tricyclic amides, processes for their preparation, and pharmaceutical compositions containing them | ADIR (FR) | 1999-07-21 | — | — | EP | disclosed |
| EP-0737670-A1 | Tricyclic amides, processes for their preparation, and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1996-10-16 | — | — | EP | disclosed |