SCHEMBL8409093

SCHEMBL8409093

CCc1cc(Br)cc(CC)c1O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 4/20 0.50
GABRB2 P47870 3/20 0.50
CYP3A4 P08684 2/20 0.43
TSHR P16473 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
GFER P55789 1/20 0.43
CYP1A2 P05177 1/20 0.42
CYP2C9 P11712 1/20 0.42
GABRB1 P18505 2/20 0.41
GABRA2 P47869 1/20 0.39
GAA P10253 1/20 0.39
DHFR P00374 1/20 0.37
ERN1 O75460 2/20 0.37
AKR1C4 P17516 1/20 0.37
AKR1C3 P42330 1/20 0.37
AKR1C2 P52895 1/20 0.37
AKR1C1 Q04828 1/20 0.37
ALOX15 P16050 1/20 0.37
ALOX12 P18054 1/20 0.37
TTR P02766 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11613709 0.88 CYP3A4 (0.56) GABRA1GABRB2CYP3A4TSHRTDP1
SCHEMBL15065038 0.88 GABRA1 (0.50) GABRA1GABRB2CYP3A4TSHRTDP1
SCHEMBL6542408 0.88 PTPN1 (0.41) GABRA1GABRB2CYP3A4TSHRTDP1
SCHEMBL1738342 0.86 SHBG (0.39) GABRA1GABRB2CYP3A4TSHRTDP1
SCHEMBL3985036 0.84 GFER (0.38) GABRA1GABRB2CYP3A4TSHRTDP1
SCHEMBL257069 0.84 ACLY (0.43) GABRA1GABRB2CYP3A4TSHRTDP1
SCHEMBL14417263 0.81 GAA (0.60) TSHRGAAERN1ALOX15ALOX12
SCHEMBL3490091 0.81 AKR1C3 (0.60) GABRA1GABRB2TSHRGABRB1GABRA2
SCHEMBL1620551 0.81 ERN1 (0.60) GFERCYP1A2ERN1
SCHEMBL10827055 0.81 PTPN1 (0.49) GABRA1GABRB2PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101497692-B Use of magnetic supported catalyst in polyphenylene oxide preparation UNIV ZHEJIANG 2011-03-16 CN claimed
CN-101942087-A Metal ion-hyperbranched polyamide amine complex catalyst and application to preparing polyphenylene oxide (PPO) in water medium UNIV ZHEJIANG 2011-01-12 CN claimed
CN-101544755-B Metallic ion-polyvinyl imidazol complex catalyst and preparation method and application thereof UNIV ZHEJIANG 2010-12-08 CN claimed
CN-101544755-A Metallic ion-polyvinyl imidazol complex catalyst and preparation method and application thereof UNIV ZHEJIANG 2009-09-30 CN claimed
CN-101497692-A Magnetic supported catalyst and use thereof in polyphenylene oxide preparation UNIV ZHEJIANG (CN) 2009-08-05 CN claimed
CN-101497693-A Metallic ion-polyamide polyamide-amine complex compound catalyst and use for preparing polyphenylene oxide in aqueous medium UNIV ZHEJIANG (CN) 2009-08-05 CN claimed
CN-102060990-A Magnetic supported catalyst and application thereof in preparing polyphenyleneoxide in aqueous medium UNIV ZHEJIANG 2011-05-18 CN disclosed
CN-101497692-B Use of magnetic supported catalyst in polyphenylene oxide preparation UNIV ZHEJIANG 2011-03-16 CN disclosed
CN-101942087-A Metal ion-hyperbranched polyamide amine complex catalyst and application to preparing polyphenylene oxide (PPO) in water medium UNIV ZHEJIANG 2011-01-12 CN disclosed
CN-101544755-B Metallic ion-polyvinyl imidazol complex catalyst and preparation method and application thereof UNIV ZHEJIANG 2010-12-08 CN disclosed
CN-101544755-A Metallic ion-polyvinyl imidazol complex catalyst and preparation method and application thereof UNIV ZHEJIANG 2009-09-30 CN disclosed
CN-101497692-A Magnetic supported catalyst and use thereof in polyphenylene oxide preparation UNIV ZHEJIANG (CN) 2009-08-05 CN disclosed
CN-101497693-A Metallic ion-polyamide polyamide-amine complex compound catalyst and use for preparing polyphenylene oxide in aqueous medium UNIV ZHEJIANG (CN) 2009-08-05 CN disclosed
US-5872137-A AROMATIC OXY DIHALOPRENE COMPOUNDS INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-02-16 US disclosed
EP-0722430-B1 DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL CO (JP) 1998-10-21 EP disclosed
EP-0722430-A1 DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1996-07-24 EP disclosed
WO-1996004228-A1 DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-02-15 WO disclosed
US-4079035-A Halophenoxyphosphazene fire retardants and polyesters containing same ETHYL CORPORATION (US) 1978-03-14 US disclosed
US-4026964-A Halophenoxyphosphazene fire retardants and polyesters containing same ETHYL CORPORATION (US) 1977-05-31 US disclosed
US-3996312-A CROSSLINKED BY A PHOSPHORUS-OXYGEN-PHOSPHORUS BOND ETHYL CORPORATION (US) 1976-12-07 US disclosed