Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8409093 | 0.86 | GABRA1 (0.50) | GFERGABRA1GABRB2CYP3A4TSHR | |
| SCHEMBL13623354 | 0.83 | SHBG (0.59) | SHBGESR1ESR2GFERGABRA1 | |
| SCHEMBL17204833 | 0.80 | CYP3A4 (0.38) | SHBGGFERGABRA1ALDH1A1CYP3A4 | |
| SCHEMBL6542408 | 0.80 | PTPN1 (0.41) | ESR1ESR2GFERGABRA1GABRB2 | |
| SCHEMBL11613709 | 0.80 | CYP3A4 (0.56) | GFERGABRA1GABRB2ALDH1A1CYP3A4 | |
| SCHEMBL15065038 | 0.80 | GABRA1 (0.50) | GFERGABRA1GABRB2CYP3A4TSHR | |
| SCHEMBL13623356 | 0.79 | PRKCE (0.46) | SHBGESR1ESR2GFERGABRA1 | |
| SCHEMBL15758556 | 0.79 | ALOX5 (0.46) | ESR1ALDH1A1CYP3A4TSHRTDP1 | |
| SCHEMBL49544 | 0.78 | CA1 (0.58) | ESR1ESR2GABRA1GABRB2ALDH1A1 | |
| SCHEMBL9749694 | 0.77 | CA1 (0.59) | SHBGESR1ESR2GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101497692-B | Use of magnetic supported catalyst in polyphenylene oxide preparation | UNIV ZHEJIANG | 2011-03-16 | — | — | CN | claimed |
| CN-101942087-A | Metal ion-hyperbranched polyamide amine complex catalyst and application to preparing polyphenylene oxide (PPO) in water medium | UNIV ZHEJIANG | 2011-01-12 | — | — | CN | claimed |
| CN-101544755-B | Metallic ion-polyvinyl imidazol complex catalyst and preparation method and application thereof | UNIV ZHEJIANG | 2010-12-08 | — | — | CN | claimed |
| CN-101544755-A | Metallic ion-polyvinyl imidazol complex catalyst and preparation method and application thereof | UNIV ZHEJIANG | 2009-09-30 | — | — | CN | claimed |
| CN-101497692-A | Magnetic supported catalyst and use thereof in polyphenylene oxide preparation | UNIV ZHEJIANG (CN) | 2009-08-05 | — | — | CN | claimed |
| CN-101497693-A | Metallic ion-polyamide polyamide-amine complex compound catalyst and use for preparing polyphenylene oxide in aqueous medium | UNIV ZHEJIANG (CN) | 2009-08-05 | — | — | CN | claimed |
| US-11807621-B2 | Compounds and compositions for use in treating skin disorders | KAMARI PHARMA LTD. (IL) | 2023-11-07 | — | — | US | disclosed |
| CN-102060990-B | Magnetic supported catalyst and application thereof in preparing polyphenyleneoxide in aqueous medium | UNIV ZHEJIANG | 2012-11-14 | — | — | CN | disclosed |
| US-8252954-B2 | Processes for the preparation of calixarene derivatives | THE CURATORS OF THE UNIVERSITY OF MISSOURI (US) | 2012-08-28 | — | — | US | disclosed |
| CN-101942087-B | Metal ion-hyperbranched polyamidoamine complex catalyst and application thereof in preparation of polyphenyl ether in aqueous medium | UNIV ZHEJIANG | 2012-05-09 | — | — | CN | disclosed |
| US-20110311485-A1 | 1,2,4-OXADIAZOLE DERIVATIVES AND THEIR THERAPEUTIC USE | ALMIRALL S.A. (ES) | 2011-12-22 | — | — | US | disclosed |
| US-20110311485-A1 | 1,2,4-OXADIAZOLE DERIVATIVES AND THEIR THERAPEUTIC USE | ALMIRALL S.A. (ES) | 2011-12-22 | — | — | US | disclosed |
| US-20110311485-A1 | 1,2,4-OXADIAZOLE DERIVATIVES AND THEIR THERAPEUTIC USE | ALMIRALL S.A. (ES) | 2011-12-22 | — | — | US | disclosed |
| EP-0824514-A1 | DIHALOPROPENE COMPOUNDS, INSECTICIDES CONTAINING THEM AS ACTIVE INGREDIENTS, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1998-02-25 | — | — | EP | disclosed |
| WO-1997028112-A1 | DIHALOPROPENE COMPOUNDS, THEIR USE AS INSECTICIDES/ACARICIDES AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-08-07 | — | — | WO | disclosed |
| WO-1997027173-A2 | DIHALOPROPENE COMPOUNDS, THEIR USE AS INSECTICIDES/ACARICIDES AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-31 | — | — | WO | disclosed |
| CN-1137265-A | Dihalopropene compounds, insecticides/acaricides containing the same and intermediates for their production | SUMITOMO CHEMICAL CO (JP) | 1996-12-04 | — | — | CN | disclosed |
| WO-1996033160-A1 | DIHALOPROPENE COMPOUNDS, INSECTICIDES CONTAINING THEM AS ACTIVE INGREDIENTS, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-10-24 | — | — | WO | disclosed |
| EP-0722430-A1 | DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-07-24 | — | — | EP | disclosed |
| WO-1996004228-A1 | DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1996-02-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110311485-A1 | 1,2,4-OXADIAZOLE DERIVATIVES AND THEIR THERAPEUTIC USE | S1PR1, S1PR2, S1PR3 | SHBG 1379/4885ESR1 1052/4885ESR2 203/4885 |
| US-11807621-B2 | Compounds and compositions for use in treating skin disorders | RDX, HAX1, F12 | SHBG 533/4885ESR1 736/4885ESR2 1390/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.