Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.33 |
| ▸ | F2R | P25116 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | RARG | P13631 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
| ▸ | TYK2 | P29597 | 1/20 | 0.30 |
| ▸ | JAK3 | P52333 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8408944 | 0.87 | NPC1 (0.47) | NPC1RAB9APOLBPARP1LMNA | |
| SCHEMBL8408943 | 0.85 | NPC1 (0.36) | NPC1RAB9APOLBACSS2PARP1 | |
| SCHEMBL8408907 | 0.85 | PARP1 (0.39) | NPC1RAB9APOLBPARP1LMNA | |
| SCHEMBL8409154 | 0.84 | NPC1 (0.35) | NPC1RAB9APOLBPARP1LMNA | |
| SCHEMBL699155 | 0.84 | NPC1 (0.47) | NPC1RAB9APOLBLMNAALDH1A1 | |
| SCHEMBL8407971 | 0.82 | NPC1 (0.35) | NPC1RAB9APOLBPARP1LMNA | |
| SCHEMBL8409167 | 0.80 | EPHX2 (0.49) | RAB9ALMNAALDH1A1SMN1; SMN2EPHX2 | |
| SCHEMBL8408911 | 0.78 | NR1H4 (0.40) | RAB9ALMNAALDH1A1SMN1; SMN2EPHX2 | |
| SCHEMBL3077803 | 0.78 | HSPA5 (0.42) | NPC1RAB9APOLBF2RLMNA | |
| SCHEMBL8962454 | 0.78 | NPC1 (0.54) | NPC1RAB9APOLBLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5935900-A | BENZOTRIAZOLE COMPOUND, DIPHENYLSULFONE ELECTRON ACCEPTOR | OJL PAPER CO., LTD. (JP) | 1999-08-10 | — | — | US | disclosed |