Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.35 |
| ▸ | RAB9A | P51151 | 5/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | HPGD | P15428 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8407971 | 0.91 | NPC1 (0.35) | NPC1RAB9APOLBPARP1LMNA | |
| SCHEMBL8408944 | 0.87 | NPC1 (0.47) | NPC1RAB9APOLBPARP1LMNA | |
| SCHEMBL8408943 | 0.85 | NPC1 (0.36) | NPC1RAB9APOLBJAK2JAK1 | |
| SCHEMBL8409283 | 0.85 | PARP1 (0.39) | NPC1RAB9APOLBPARP1LMNA | |
| SCHEMBL8409164 | 0.84 | NPC1 (0.35) | NPC1RAB9APOLBJAK2JAK1 | |
| SCHEMBL8409160 | 0.80 | TTR (0.40) | NPC1RAB9ALMNAMAPTSMN1; SMN2 | |
| SCHEMBL8409285 | 0.78 | MAP3K7 (0.39) | POLBLMNAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL26658010 | 0.78 | NPC1 (0.46) | NPC1RAB9APOLBLMNAALDH1A1 | |
| SCHEMBL8406938 | 0.76 | NPC1 (0.37) | NPC1RAB9APOLBPARP1LMNA | |
| SCHEMBL8055374 | 0.76 | TTR (0.44) | NPC1RAB9APOLBLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5935900-A | BENZOTRIAZOLE COMPOUND, DIPHENYLSULFONE ELECTRON ACCEPTOR | OJL PAPER CO., LTD. (JP) | 1999-08-10 | — | — | US | disclosed |