Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.35 |
| ▸ | RAB9A | P51151 | 5/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8409154 | 0.91 | NPC1 (0.35) | NPC1RAB9APOLBLMNAALDH1A1 | |
| SCHEMBL8408944 | 0.86 | NPC1 (0.47) | NPC1RAB9APOLBLMNAALDH1A1 | |
| SCHEMBL8406938 | 0.85 | NPC1 (0.37) | NPC1RAB9APOLBLMNAALDH1A1 | |
| SCHEMBL8408943 | 0.84 | NPC1 (0.36) | NPC1RAB9APOLBLMNAALDH1A1 | |
| SCHEMBL8409164 | 0.82 | NPC1 (0.35) | NPC1RAB9APOLBLMNAALDH1A1 | |
| SCHEMBL8407973 | 0.81 | TTR (0.38) | NPC1RAB9APOLBLMNAMAPT | |
| SCHEMBL8406942 | 0.80 | MAP3K7 (0.39) | LMNAALDH1A1KDM4EL3MBTL1MEN1 | |
| SCHEMBL8061708 | 0.77 | TTR (0.41) | NPC1RAB9APOLBLMNAALDH1A1 | |
| SCHEMBL8409283 | 0.76 | PARP1 (0.39) | NPC1RAB9APOLBLMNAALDH1A1 | |
| SCHEMBL20363907 | 0.74 | NPC1 (0.47) | NPC1RAB9APOLBLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5935900-A | BENZOTRIAZOLE COMPOUND, DIPHENYLSULFONE ELECTRON ACCEPTOR | OJL PAPER CO., LTD. (JP) | 1999-08-10 | — | — | US | disclosed |