Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 8/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 7/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8061576 | 0.95 | LMNA (0.47) | EPHX2NR1H4LMNARAB9AEGFR | |
| SCHEMBL8408911 | 0.92 | NR1H4 (0.40) | EPHX2NR1H4LMNARAB9AEGFR | |
| SCHEMBL8061717 | 0.89 | TTR (0.42) | EPHX2NR1H4LMNARAB9AEGFR | |
| SCHEMBL8408952 | 0.87 | NPC1 (0.47) | EPHX2NR1H4LMNARAB9ATTR | |
| SCHEMBL9408737 | 0.85 | RAB9A (0.40) | EPHX2LMNARAB9AEGFRTTR | |
| SCHEMBL8408950 | 0.85 | TTR (0.41) | EPHX2NR1H4LMNARAB9ATTR | |
| SCHEMBL8409160 | 0.84 | TTR (0.40) | EPHX2NR1H4LMNARAB9ATTR | |
| SCHEMBL8407973 | 0.82 | TTR (0.38) | EPHX2NR1H4LMNARAB9ATTR | |
| SCHEMBL11396584 | 0.81 | RAB9A (0.38) | LMNARAB9AEGFRTTRBTK | |
| SCHEMBL8043991 | 0.81 | NPC1 (0.52) | LMNARAB9ATTRALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5935900-A | BENZOTRIAZOLE COMPOUND, DIPHENYLSULFONE ELECTRON ACCEPTOR | OJL PAPER CO., LTD. (JP) | 1999-08-10 | — | — | US | disclosed |