Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX2 | Q96LB1 | 4/20 | 1.00 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.83 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.69 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.69 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.64 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.64 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1261490 | 1.00 | MRGPRX2 (1.00) | MRGPRX2OPRM1OPRD1OPRK1ADRB1 | |
| SCHEMBL6753388 | 1.00 | MRGPRX2 (1.00) | MRGPRX2OPRM1OPRD1OPRK1ADRB1 | |
| SCHEMBL3017103 | 0.94 | MRGPRX2 (0.89) | MRGPRX2OPRM1OPRD1OPRK1 | |
| SCHEMBL2171816 | 0.94 | MRGPRX2 (0.89) | MRGPRX2OPRM1OPRD1OPRK1 | |
| Morphine Glucuronide SCHEMBL6754812 | 0.91 | OPRM1 (1.00) | MRGPRX2OPRM1OPRD1OPRK1 | |
| Morphine Glucuronide SCHEMBL13268600 | 0.91 | OPRM1 (1.00) | MRGPRX2OPRM1OPRD1OPRK1 | |
| Morphine Glucuronide SCHEMBL152647 | 0.91 | OPRM1 (1.00) | MRGPRX2OPRM1OPRD1OPRK1 | |
| Morphine Glucuronide SCHEMBL1743681 | 0.91 | OPRM1 (1.00) | MRGPRX2OPRM1OPRD1OPRK1 | |
| Morphine Glucuronide SCHEMBL13245908 | 0.91 | OPRM1 (1.00) | MRGPRX2OPRM1OPRD1OPRK1 | |
| Morphine Glucuronide SCHEMBL13267437 | 0.91 | OPRM1 (1.00) | MRGPRX2OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170267985-A1 | MUTANT LACTOBACILLUS BETA-GLUCURONIDASE ENZYMES WITH ENHANCED ENZYMATIC ACTIVITY | INTEGRATED MICRO-CHROMATOGRAPHY SYSTEMS, INC. | 2017-09-21 | — | — | US | claimed |
| US-20160237415-A1 | MUTANT STAPHYLOCOCCUS BETA-GLUCURONIDASE ENZYMES WITH ENHANCED ENZYMATIC ACTIVITY | INTEGRATED MICRO-CHROMATOGRAPHY SYSTEMS, INC. | 2016-08-18 | — | — | US | claimed |
| US-9920306-B2 | Mutant β-glucuronidase enzymes with enhanced enzymatic activity | INTEGRATED MICRO-CHROMATOGRAPHY SYSTEMS, LLC (US) | 2018-03-20 | — | — | US | disclosed |
| US-9909111-B2 | Mutant lactobacillus beta-glucuronidase enzymes with enhanced enzymatic activity | INTEGRATED MICRO-CHROMATOGRAPHY SYSTEMS (US) | 2018-03-06 | — | — | US | disclosed |
| US-20170267985-A1 | MUTANT LACTOBACILLUS BETA-GLUCURONIDASE ENZYMES WITH ENHANCED ENZYMATIC ACTIVITY | INTEGRATED MICRO-CHROMATOGRAPHY SYSTEMS, INC. | 2017-09-21 | — | — | US | disclosed |
| US-9719075-B2 | Mutant Staphylococcus beta-glucuronidase enzymes with enhanced enzymatic activity | INTEGRATED MICRO-CHROMATOGRAPHY SYSTEMS (US) | 2017-08-01 | — | — | US | disclosed |
| US-20160237415-A1 | MUTANT STAPHYLOCOCCUS BETA-GLUCURONIDASE ENZYMES WITH ENHANCED ENZYMATIC ACTIVITY | INTEGRATED MICRO-CHROMATOGRAPHY SYSTEMS, INC. | 2016-08-18 | — | — | US | disclosed |
| US-20160090582-A1 | MUTANT BETA-GLUCURONIDASE ENZYMES WITH ENHANCED ENZYMATIC ACTIVITY | INTEGRATED MICRO-CHROMATOGRAPHY SYSTEMS, INC. | 2016-03-31 | — | — | US | disclosed |
| US-5908927-A | Synthesis of deuterated opiate glucuronides | HIGH STANDARD PRODUCTS CORPORATION (US) | 1999-06-01 | — | — | US | disclosed |
| US-5908927-A | Synthesis of deuterated opiate glucuronides | HIGH STANDARD PRODUCTS CORPORATION (US) | 1999-06-01 | — | — | US | disclosed |