SCHEMBL6753388

SCHEMBL6753388

COc1ccc2c3c1O[C@H]1[C@@H](O[C@@H]4O[C@H](C(=O)O)[C@@H](O)[C@H](O)[C@H]4O)C=C[C@H]4[C@@H](C2)N(C)CC[C@@]341

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MRGPRX2 Q96LB1 4/20 1.00
OPRM1 P35372 5/20 0.83
OPRD1 P41143 3/20 0.69
OPRK1 P41145 3/20 0.69
ADRB1 P08588 1/20 0.64
PDE4D Q08499 1/20 0.64
PDE3A Q14432 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1261490 1.00 MRGPRX2 (1.00) MRGPRX2OPRM1OPRD1OPRK1ADRB1
SCHEMBL8409352 1.00 MRGPRX2 (1.00) MRGPRX2OPRM1OPRD1OPRK1ADRB1
SCHEMBL3017103 0.94 MRGPRX2 (0.89) MRGPRX2OPRM1OPRD1OPRK1
SCHEMBL2171816 0.94 MRGPRX2 (0.89) MRGPRX2OPRM1OPRD1OPRK1
Morphine Glucuronide SCHEMBL6754812 0.91 OPRM1 (1.00) MRGPRX2OPRM1OPRD1OPRK1
Morphine Glucuronide SCHEMBL13268600 0.91 OPRM1 (1.00) MRGPRX2OPRM1OPRD1OPRK1
Morphine Glucuronide SCHEMBL152647 0.91 OPRM1 (1.00) MRGPRX2OPRM1OPRD1OPRK1
Morphine Glucuronide SCHEMBL1743681 0.91 OPRM1 (1.00) MRGPRX2OPRM1OPRD1OPRK1
Morphine Glucuronide SCHEMBL13245908 0.91 OPRM1 (1.00) MRGPRX2OPRM1OPRD1OPRK1
Morphine Glucuronide SCHEMBL13267437 0.91 OPRM1 (1.00) MRGPRX2OPRM1OPRD1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4722379-A1 METHOD FOR DETERMINING THE CONTENT OF AT LEAST ONE ANALYTE IN A SAMPLE AND ANALYSIS KIT FOR USE IN SAID METHOD Chromsystems Instruments & Chemicals GmbH (DE) 2026-04-08 EP claimed
EP-4722379-A1 METHOD FOR DETERMINING THE CONTENT OF AT LEAST ONE ANALYTE IN A SAMPLE AND ANALYSIS KIT FOR USE IN SAID METHOD Chromsystems Instruments & Chemicals GmbH (DE) 2026-04-08 EP disclosed
US-11571390-B2 Abuse deterrent compositions and methods of use Othemo Life Sciences, Inc. (US) 2023-02-07 US disclosed
WO-2022217051-A1 EFFICIENTLY TRAINING AND EVALUATING PATIENT TREATMENT PREDICTION MODELS UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2022-10-13 WO disclosed
US-20220328198-A1 EFFICIENTLY TRAINING AND EVALUATING PATIENT TREATMENT PREDICTION MODELS UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION 2022-10-13 US disclosed
US-6737518-B1 REACTING 4,5-EPOXYMORPHINAN-6-OLS WITH BROMOGLUCURONIDES IN THE PRESENCE OF ZINC BROMIDE; DEPROTECTING END PRODUCTS TO MAKE MORPHINE-6-BETA-D-GLUCURONIDE (M6G) CENES LIMITED (GB) 2004-05-18 US disclosed
US-20040053854-A1 Process for preparation of 4,5-Epoxymorphinan-6-oxyglucuronides CENES LIMITED (GB) 2004-03-18 US disclosed
EP-1077985-A1 PROCESS FOR PREPARATION OF 4,5-EPOXYMORPHINAN-6-OXYGLUCURONIDES CeNes Limited (GB) 2001-02-28 EP disclosed
WO-1999058545-A1 PROCESS FOR PREPARATION OF 4,5-EPOXYMORPHINAN-6-OXYGLUCURONIDES CENES LIMITED (GB) 1999-11-18 WO disclosed
US-5908927-A Synthesis of deuterated opiate glucuronides HIGH STANDARD PRODUCTS CORPORATION (US) 1999-06-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040053854-A1 Process for preparation of 4,5-Epoxymorphinan-6-oxyglucuronides OGFR, OSTC, GALE MRGPRX2 399/4885OPRM1 4/4885OPRD1 21/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.