Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.57 |
| ▸ | P2RX3 | P56373 | 7/20 | 0.50 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.47 |
| ▸ | ACACB | O00763 | 3/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
| ▸ | FPR2 | P25090 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8411968 | 0.83 | OPRM1 (0.57) | OPRM1P2RX3ACACBL3MBTL1OPRD1 | |
| SCHEMBL3177956 | 0.83 | OPRM1 (0.58) | OPRM1P2RX3EGLN1ACACBPDE4B | |
| SCHEMBL6917099 | 0.82 | SRD5A2 (0.57) | SRD5A2MMP2 | |
| SCHEMBL1222601 | 0.82 | OPRM1 (0.51) | OPRM1P2RX3ACACBPDE4BSRD5A2 | |
| SCHEMBL8016836 | 0.80 | OPRM1 (0.58) | OPRM1P2RX3EGLN1ACACBPDE4B | |
| SCHEMBL6161241 | 0.80 | OPRM1 (0.58) | OPRM1P2RX3ACACBPDE4BGAA | |
| SCHEMBL3692227 | 0.78 | OPRM1 (0.62) | OPRM1P2RX3ACACBPDE4BGAA | |
| SCHEMBL3693450 | 0.78 | PARP10 (0.68) | OPRM1PDE4BFPR2SCN9AOPRD1 | |
| SCHEMBL6158872 | 0.78 | OPRM1 (0.61) | OPRM1ACACBPDE4B | |
| SCHEMBL7452934 | 0.77 | SRD5A2 (0.54) | OPRM1EGLN1ACACBSRD5A2OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0822930-B1 | PYRIDINE DERIVATIVE AND PESTICIDE | KUMIAI CHEMICAL INDUSTRY CO (JP) | 1999-07-28 | — | — | EP | disclosed |
| US-5763463-A | Pyridine compounds which are useful as pesticides | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1998-06-09 | — | — | US | disclosed |
| EP-0822930-A1 | PYRIDINE DERIVATIVE AND PESTICIDE | KumaiI Chemical Industry Co., Ltd. (JP) | 1998-02-11 | — | — | EP | disclosed |