Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 13/20 | 0.40 |
| ▸ | AR | P10275 | 11/20 | 0.40 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 12/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8407122 | 0.91 | PGR (0.40) | PGRARNR3C2NR3C1CYP19A1 | |
| SCHEMBL8407111 | 0.86 | NR3C1 (0.38) | PGRARNR3C2NR3C1TDP1 | |
| SCHEMBL8409910 | 0.86 | PGR (0.37) | PGRARNR3C2NR3C1TDP1 | |
| SCHEMBL8619892 | 0.84 | NR3C1 (0.46) | PGRARNR3C2NR3C1TDP1 | |
| SCHEMBL8409857 | 0.84 | NR3C1 (0.38) | PGRARNR3C2NR3C1CYP3A4 | |
| SCHEMBL8767796 | 0.83 | PGR (0.55) | PGRARNR3C1LMNACYP3A4 | |
| SCHEMBL8407061 | 0.80 | PGR (0.37) | PGRARNR3C2NR3C1LMNA | |
| SCHEMBL9649843 | 0.75 | PGR (0.38) | PGRARNR3C2NR3C1TDP1 | |
| SCHEMBL8407237 | 0.75 | NR3C1 (0.54) | PGRARNR3C2NR3C1TDP1 | |
| SCHEMBL8622523 | 0.74 | NR3C1 (0.59) | PGRARNR3C2NR3C1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0565553-B1 | 6,7-MODIFIED 11$g(b)-ARYL-4-ESTRENES | SCHERING AG (DE) | 1999-07-21 | — | — | EP | disclosed |
| US-5843931-A | 6,7-modified 11β-aryl-4-oestrenes | SHERING AKTIENGESELLSCHAFT (DE) | 1998-12-01 | — | — | US | disclosed |