Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 12/20 | 0.35 |
| ▸ | AR | P10275 | 11/20 | 0.35 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 10/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8407061 | 0.89 | PGR (0.37) | PGRARNR3C2NR3C1CYP3A4 | |
| SCHEMBL8407053 | 0.89 | NR3C1 (0.36) | PGRARNR3C2NR3C1CYP3A4 | |
| SCHEMBL9649843 | 0.85 | PGR (0.38) | PGRARNR3C2NR3C1CYP3A4 | |
| SCHEMBL8407284 | 0.84 | NR3C1 (0.41) | PGRARNR3C2NR3C1CYP3A4 | |
| SCHEMBL8536675 | 0.83 | PGR (0.50) | PGRARNR3C1CYP3A4 | |
| SCHEMBL8768221 | 0.83 | PGR (0.50) | PGRARNR3C1CYP3A4 | |
| SCHEMBL9019818 | 0.83 | PGR (0.50) | PGRARNR3C1CYP3A4 | |
| SCHEMBL7200581 | 0.83 | PGR (0.50) | PGRARNR3C1CYP3A4 | |
| SCHEMBL8408969 | 0.83 | NR3C1 (0.48) | PGRARNR3C2NR3C1CYP3A4 | |
| SCHEMBL8653821 | 0.79 | PGR (0.47) | PGRARNR3C1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0565553-B1 | 6,7-MODIFIED 11$g(b)-ARYL-4-ESTRENES | SCHERING AG (DE) | 1999-07-21 | — | — | EP | claimed |
| EP-0565553-B1 | 6,7-MODIFIED 11$g(b)-ARYL-4-ESTRENES | SCHERING AG (DE) | 1999-07-21 | — | — | EP | disclosed |