Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.59 |
| ▸ | MMP1 | P03956 | 2/20 | 0.57 |
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | BMP1 | P13497 | 1/20 | 0.53 |
| ▸ | CCKBR | P32239 | 3/20 | 0.53 |
| ▸ | MMP2 | P08253 | 1/20 | 0.53 |
| ▸ | MMP8 | P22894 | 1/20 | 0.53 |
| ▸ | CDC25B | P30305 | 1/20 | 0.52 |
| ▸ | ACE | P12821 | 1/20 | 0.52 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 1/20 | 0.51 |
| ▸ | ECE1 | P42892 | 1/20 | 0.51 |
| ▸ | PRKACB | P22694 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7402598 | 0.87 | MMP1 (0.52) | EPHX2MMP1CCKBRMMP2MMP8 | |
| SCHEMBL8408670 | 0.87 | EPHX2 (0.48) | EPHX2MMP1BMP1CCKBRMMP2 | |
| SCHEMBL29791638 | 0.87 | NPBWR1 (0.60) | CCKBRPRKACB | |
| SCHEMBL8411410 | 0.86 | MMP1 (0.49) | MMP1CCKBRMMP2MMP8ACE | |
| SCHEMBL30129802 | 0.86 | CCKAR (0.54) | MMP1CCKBRACEERAP2 | |
| SCHEMBL16161422 | 0.86 | CCKAR (0.54) | MMP1CCKBRACEERAP2 | |
| SCHEMBL16359369 | 0.86 | MEN1 (0.57) | EPHX2BMP1ECE1PRKACB | |
| SCHEMBL16620991 | 0.85 | PPARG (0.68) | EPHX2PPARGACEERAP2 | |
| SCHEMBL30492107 | 0.85 | PRKACB (0.57) | EPHX2PPARGBMP1PRKACB | |
| SCHEMBL29485117 | 0.84 | PRKACB (0.55) | EPHX2PPARGBMP1ACEPRKACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0454651-B1 | Novel platelet-aggregation inhibitors | MONSANTO CO (US) | 1999-07-28 | — | — | EP | claimed |
| EP-0454651-A2 | Novel platelet-aggregation inhibitors | MONSANTO COMPANY (US) | 1991-10-30 | — | — | EP | claimed |
| US-5037808-A | Indolyl platelet-aggregation inhibitors | MONSANTO CO. (US) | 1991-08-06 | — | — | US | claimed |
| EP-0454651-B1 | Novel platelet-aggregation inhibitors | MONSANTO CO (US) | 1999-07-28 | — | — | EP | disclosed |
| US-5091396-A | Guanidinoalkanoylaspartylpyridine derivatives; anticoagulants | MONSANTO CO. (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0454651-A2 | Novel platelet-aggregation inhibitors | MONSANTO COMPANY (US) | 1991-10-30 | — | — | EP | disclosed |
| US-5037808-A | Indolyl platelet-aggregation inhibitors | MONSANTO CO. (US) | 1991-08-06 | — | — | US | disclosed |