Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 2/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
| ▸ | MMP8 | P22894 | 1/20 | 0.52 |
| ▸ | ACE | P12821 | 2/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CDC25B | P30305 | 1/20 | 0.48 |
| ▸ | ECE1 | P42892 | 3/20 | 0.48 |
| ▸ | CCKBR | P32239 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8410913 | 0.87 | EPHX2 (0.59) | MMP1MMP2MMP8ACEEPHX2 | |
| SCHEMBL7398177 | 0.84 | LMNA (0.45) | EPHX2KMT2A | |
| SCHEMBL7397648 | 0.84 | LMNA (0.45) | EPHX2KMT2A | |
| SCHEMBL8411410 | 0.84 | MMP1 (0.49) | MMP1MMP2MMP8ACELTA4H | |
| SCHEMBL31074790 | 0.83 | MMP1 (0.51) | MMP1MMP2MMP8ACE | |
| SCHEMBL31074780 | 0.82 | ERAP2 (0.51) | MMP1MMP2MMP8ACECCKBR | |
| SCHEMBL31484223 | 0.82 | ERAP2 (0.51) | MMP1MMP2MMP8ACECCKBR | |
| SCHEMBL30391075 | 0.82 | ACE (0.57) | ACEECE1 | |
| SCHEMBL30688662 | 0.81 | MMP1 (0.51) | MMP1MMP2MMP8ACEKMT2A | |
| SCHEMBL30053160 | 0.81 | KISS1R (0.50) | MMP1MMP2MMP8ACEKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5614539-A | ANTICOAGULANTS | G. D. SEARLE & CO. (US) | 1997-03-25 | — | — | US | claimed |
| WO-1994021602-A1 | UREA DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1994-09-29 | — | — | WO | claimed |
| US-5614539-A | ANTICOAGULANTS | G. D. SEARLE & CO. (US) | 1997-03-25 | — | — | US | disclosed |
| WO-1994021602-A1 | UREA DERIVATIVES USEFUL AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1994-09-29 | — | — | WO | disclosed |