Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 2/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | MMP8 | P22894 | 1/20 | 0.49 |
| ▸ | ACE | P12821 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.46 |
| ▸ | MME | P08473 | 1/20 | 0.46 |
| ▸ | CCKBR | P32239 | 2/20 | 0.46 |
| ▸ | CCKAR | P32238 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | ECE1 | P42892 | 3/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8410913 | 0.86 | EPHX2 (0.59) | MMP1MMP2MMP8ACEERAP2 | |
| SCHEMBL7402598 | 0.84 | MMP1 (0.52) | MMP1MMP2MMP8ACECCKBR | |
| SCHEMBL16161422 | 0.81 | CCKAR (0.54) | MMP1ACEERAP2CCKBRCCKAR | |
| SCHEMBL30129802 | 0.81 | CCKAR (0.54) | MMP1ACEERAP2CCKBRCCKAR | |
| SCHEMBL31074780 | 0.81 | ERAP2 (0.51) | MMP1MMP2MMP8ACEERAP2 | |
| SCHEMBL31484223 | 0.81 | ERAP2 (0.51) | MMP1MMP2MMP8ACEERAP2 | |
| SCHEMBL30053160 | 0.80 | KISS1R (0.50) | MMP1MMP2MMP8ACEERAP2 | |
| SCHEMBL31074790 | 0.80 | MMP1 (0.51) | MMP1MMP2MMP8ACEERAP2 | |
| SCHEMBL31145136 | 0.80 | ACE (0.54) | ACEERAP2ECE1 | |
| SCHEMBL7329586 | 0.79 | HDAC3 (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0454651-B1 | Novel platelet-aggregation inhibitors | MONSANTO CO (US) | 1999-07-28 | — | — | EP | claimed |
| EP-0454651-A2 | Novel platelet-aggregation inhibitors | MONSANTO COMPANY (US) | 1991-10-30 | — | — | EP | claimed |
| US-5037808-A | Indolyl platelet-aggregation inhibitors | MONSANTO CO. (US) | 1991-08-06 | — | — | US | claimed |
| EP-0454651-B1 | Novel platelet-aggregation inhibitors | MONSANTO CO (US) | 1999-07-28 | — | — | EP | disclosed |
| US-5091396-A | Guanidinoalkanoylaspartylpyridine derivatives; anticoagulants | MONSANTO CO. (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0454651-A2 | Novel platelet-aggregation inhibitors | MONSANTO COMPANY (US) | 1991-10-30 | — | — | EP | disclosed |
| US-5037808-A | Indolyl platelet-aggregation inhibitors | MONSANTO CO. (US) | 1991-08-06 | — | — | US | disclosed |