Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8339074 | 0.92 | ALDH1A1 (0.44) | ALDH1A1LMNAHSD17B10MAPTGLO1 | |
| SCHEMBL25405030 | 0.83 | MAPT (0.52) | ALDH1A1LMNAHSD17B10MAPTGLO1 | |
| SCHEMBL11321817 | 0.83 | ALDH1A1 (0.50) | ALDH1A1LMNAHSD17B10MAPTGLO1 | |
| SCHEMBL8825077 | 0.81 | ALDH1A1 (0.46) | ALDH1A1LMNAHSD17B10MAPTGLO1 | |
| SCHEMBL11329782 | 0.81 | ALOX15 (0.39) | ALDH1A1LMNAHSD17B10MAPTGLO1 | |
| SCHEMBL8825080 | 0.81 | ALDH1A1 (0.46) | ALDH1A1LMNAHSD17B10MAPTGLO1 | |
| SCHEMBL6934179 | 0.79 | ALDH1A1 (0.44) | ALDH1A1LMNAHSD17B10MAPTGLO1 | |
| SCHEMBL8584723 | 0.78 | TSHR (0.52) | ALDH1A1MAPTNPSR1TSHRMEN1 | |
| SCHEMBL4836138 | 0.77 | ALDH1A1 (0.42) | ALDH1A1LMNAHSD17B10MAPTGLO1 | |
| SCHEMBL11325447 | 0.76 | GLO1 (0.41) | ALDH1A1LMNAHSD17B10MAPTGLO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0811602-B1 | Process for the preparation of salts of the aminomalonic ester | HUELS CHEMISCHE WERKE AG (DE) | 1999-07-28 | — | — | EP | disclosed |
| US-5847197-A | Process for the preparation of aminomalonic acid ester salts | HUELS AKTIENGESELLSCHAFT (DE) | 1998-12-08 | — | — | US | disclosed |
| EP-0811602-A1 | Process for the preparation of salts of the aminomalonic ester | HÜLS AKTIENGESELLSCHAFT (DE) | 1997-12-10 | — | — | EP | disclosed |