Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 7/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | NSD2 | O96028 | 2/20 | 0.42 |
| ▸ | VNN1 | O95497 | 1/20 | 0.40 |
| ▸ | FPR1 | P21462 | 4/20 | 0.40 |
| ▸ | FPR2 | P25090 | 4/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28867116 | 0.79 | EPHX1 (0.42) | KDM4E | |
| SCHEMBL8411267 | 0.77 | NSD2 (0.49) | MAOAMAOBCYP19A1EPHX2NSD2 | |
| SCHEMBL27545889 | 0.76 | PDE4A (0.38) | CYP19A1KDM4E | |
| SCHEMBL25772910 | 0.74 | CA2 (0.39) | CYP19A1EPHX2KDM4ECYP11B1CYP11B2 | |
| SCHEMBL27516633 | 0.72 | CNR2 (0.38) | MAOAMAOB | |
| SCHEMBL5751018 | 0.72 | MAOA (0.44) | MAOAMAOBCYP19A1EPHX2NSD2 | |
| SCHEMBL5751287 | 0.71 | EPHX2 (0.47) | MAOAMAOBEPHX2NSD2VNN1 | |
| SCHEMBL7935598 | 0.70 | MAOA (0.61) | MAOAMAOBCYP19A1NSD2VNN1 | |
| SCHEMBL14542515 | 0.70 | LOXL2 (0.48) | CYP19A1KCNH2CYP11B1CYP11B2 | |
| SCHEMBL1972799 | 0.70 | LOXL2 (0.48) | CYP19A1KCNH2CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5962495-A | ESTROGEN SENSITIVE DISEASES; BREAST CANCER; PROSTATE TUMORS | RISTO ARVO SAKARI LAMMINTAUSTA (FI) | 1999-10-05 | — | — | US | disclosed |
| US-5703109-A | CYANOPHENYL-1,2,4-TRIAZOLE DERIVATIVE | Oy, Orion-yhtyma (FI) | 1997-12-30 | — | — | US | disclosed |
| EP-0674626-A1 | NOVEL SELECTIVE AROMATASE INHIBITING COMPOUNDS | ORION-YHTYMÄ OY (FI) | 1995-10-04 | — | — | EP | disclosed |
| WO-1994013645-A1 | NOVEL SELECTIVE AROMATASE INHIBITING COMPOUNDS | Orion-Yhtymä Oy (FI) | 1994-06-23 | — | — | WO | disclosed |