Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.38 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28867116 | 0.85 | EPHX1 (0.42) | CNR2PPARGPPARA | |
| SCHEMBL9108230 | 0.84 | CTSB (0.36) | CNR2HDAC4HDAC7HDAC5 | |
| SCHEMBL28805788 | 0.83 | OPRM1 (0.39) | CNR2HDAC4HDAC7HDAC5CES2 | |
| SCHEMBL27608063 | 0.81 | NFE2L2 (0.43) | CNR2NFE2L2CNR1 | |
| SCHEMBL27586696 | 0.78 | HDAC4 (0.41) | CNR2HDAC4HDAC7HDAC5SLC6A9 | |
| SCHEMBL30435064 | 0.78 | HDAC4 (0.45) | CNR2HDAC4HDAC7HDAC5SLC6A9 | |
| SCHEMBL25772213 | 0.78 | HDAC4 (0.45) | CNR2HDAC4HDAC7HDAC5SLC6A9 | |
| SCHEMBL27695773 | 0.77 | LOXL2 (0.37) | MAOAMAOB | |
| SCHEMBL27907592 | 0.75 | HDAC4 (0.39) | CNR2HDAC4HDAC7HDAC5CES2 | |
| SCHEMBL27516632 | 0.75 | HDAC4 (0.46) | CNR2HDAC4HDAC7HDAC5SLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1951939-A | Novel pyrrole derivatives as pharmaceutical agents | LILLY CO ELI (US) | 2007-04-25 | — | — | CN | disclosed |
| CN-1269820-C | Novel pyrrole derivatives as medicaments | LILLY CO ELI (US) | 2006-08-16 | — | — | CN | disclosed |
| CN-1511157-A | Novel pyrrole derivatives as medicaments | — | 2004-07-07 | — | — | CN | disclosed |