Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 2/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TMPRSS15 | P98073 | 2/20 | 0.39 |
| ▸ | ACR | P10323 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12228517 | 0.77 | LTA4H (0.41) | PRSS1PRSS2PRSS3TDP1KDM4E | |
| SCHEMBL12782035 | 0.76 | PRSS1 (0.45) | PRSS1PRSS2PRSS3TDP1KDM4E | |
| SCHEMBL3596957 | 0.76 | CA1 (0.47) | PRSS1PRSS2PRSS3TDP1KDM4E | |
| SCHEMBL8483797 | 0.75 | CA4 (0.42) | PRSS1PRSS2PRSS3TDP1KDM4E | |
| SCHEMBL21842904 | 0.75 | TDP1 (0.39) | PRSS1PRSS2PRSS3TDP1KDM4E | |
| SCHEMBL2468563 | 0.72 | TMPRSS15 (0.42) | TDP1KDM4EMAPTCA1CA2 | |
| SCHEMBL22202131 | 0.72 | MAPT (0.38) | PRSS1PRSS2PRSS3TDP1KDM4E | |
| SCHEMBL9002537 | 0.70 | GAA (0.54) | TDP1KDM4EMAPTTSHRHPGD | |
| SCHEMBL2461841 | 0.70 | PARP10 (0.39) | PRSS1TDP1LTA4HTSHRTMPRSS15 | |
| SCHEMBL19633119 | 0.70 | LTA4H (0.40) | PRSS1PRSS2PRSS3TDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130018043-A1 | AMINOMETHYL QUINOLONE COMPOUNDS | BILOTTA JOSEPH A (US) | 2013-01-17 | — | — | US | disclosed |
| US-5968934-A | TREATMENT OF PAIN, INFLAMMATION, MIGRAINES, EMESIS AND POSTHERAPEUTIC NEURALGIA | MERCK SHARP & DOHME LTD. (GB) | 1999-10-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130018043-A1 | AMINOMETHYL QUINOLONE COMPOUNDS | MAP3K1, MAP3K11, MAP3K5 | PRSS1 3434/4885PRSS2 4154/4885PRSS3 4357/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.