Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | HTR7 | P34969 | 2/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8413134 | 0.85 | TP53 (0.39) | TP53SMN1; SMN2NPC1LMNARAB9A | |
| SCHEMBL8413103 | 0.83 | L3MBTL1 (0.41) | TP53SMN1; SMN2NPC1LMNARAB9A | |
| SCHEMBL8412328 | 0.80 | NPC1 (0.41) | TP53SMN1; SMN2NPC1LMNARAB9A | |
| SCHEMBL8412378 | 0.78 | TP53 (0.45) | TP53SMN1; SMN2NPC1LMNARAB9A | |
| SCHEMBL8413577 | 0.77 | MAPT (0.40) | NPC1LMNAUSP2MAPK1MAPT | |
| SCHEMBL8413528 | 0.77 | TP53 (0.53) | TP53HTR1AHTR7DRD2DRD4 | |
| SCHEMBL8411656 | 0.76 | L3MBTL1 (0.42) | SMN1; SMN2LMNAHTR1AHTR7ADRA2A | |
| SCHEMBL8413001 | 0.75 | L3MBTL1 (0.41) | SMN1; SMN2LMNAHTR1AHTR7ADRA2A | |
| SCHEMBL8412349 | 0.74 | L3MBTL1 (0.42) | SMN1; SMN2LMNAHTR1AHTR7ADRA2A | |
| SCHEMBL8413761 | 0.74 | HTR7 (0.39) | TP53SMN1; SMN2NPC1LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5874429-A | ANTIISCHEMIC AGENTS; CEREBROVASCULAR DISORDERS; CIRCULATORY IDSORDERS | SUNTORY LIMITED (JP) | 1999-02-23 | — | — | US | disclosed |