Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.44 |
| ▸ | VCAM1 | P19320 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.42 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.42 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30471243 | 1.00 | GPR35 (0.47) | GPR35TDP1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL8410224 | 0.86 | GRIN2D (0.49) | GPR35TDP1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL1626726 | 0.85 | ALDH1A1 (0.44) | GPR35TDP1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL10597548 | 0.85 | TDP1 (0.46) | GPR35TDP1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL8082966 | 0.84 | GPR35 (0.56) | GPR35TDP1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL4592068 | 0.79 | POLB (0.44) | TDP1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL4922982 | 0.78 | TDP1 (0.60) | TDP1VCAM1ALDH1A1TSHRMAPK1 | |
| SCHEMBL8932007 | 0.77 | GPR35 (0.43) | GPR35TDP1VCAM1ALDH1A1TSHR | |
| SCHEMBL29939725 | 0.76 | TDP1 (0.61) | GPR35TDP1VCAM1ALDH1A1TSHR | |
| SCHEMBL3650611 | 0.76 | TDP1 (0.61) | GPR35TDP1VCAM1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116283597-A | Preparation method of color photographic paper raw material 2,3, 5-trichloro-4-ethylnitrobenzene | 沈阳感光化工研究院有限公司 | 2023-06-23 | — | — | CN | claimed |
| CN-116283597-A | Preparation method of color photographic paper raw material 2,3, 5-trichloro-4-ethylnitrobenzene | 沈阳感光化工研究院有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-116283597-A | Preparation method of color photographic paper raw material 2,3, 5-trichloro-4-ethylnitrobenzene | 沈阳感光化工研究院有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-116283597-A | Preparation method of color photographic paper raw material 2,3, 5-trichloro-4-ethylnitrobenzene | 沈阳感光化工研究院有限公司 | 2023-06-23 | — | — | CN | disclosed |
| EP-0718277-B1 | Method for producing 5-substituted-2-acylaminophenols, and 5-alkyl-2-acylaminophenol compound and N-acyl-N-(4-alkyl-phenyl)hydroxylamine compound | FUJI PHOTO FILM CO LTD (JP) | 1999-07-21 | — | — | EP | disclosed |
| EP-0718277-A1 | Method for producing 5-substituted-2-acylaminophenols, and 5-alkyl-2-acylaminophenol compound and N-acyl-N-(4-alkyl-phenyl)hydroxylamine compound | FUJI PHOTO FILM CO., LTD. (JP) | 1996-06-26 | — | — | EP | disclosed |
| US-5441987-A | Antifungal agent | MERCK & CO., INC. (US) | 1995-08-15 | — | — | US | disclosed |
| EP-0473464-B1 | Process for preparing 2-4-dichloro-3-alkyl-6-nitrophenols | TAOKA CHEMICAL CO LTD (JP) | 1995-06-14 | — | — | EP | disclosed |
| US-5304485-A | Fungicide from Sporormiella culture | MERCK & CO., INC. (US) | 1994-04-19 | — | — | US | disclosed |
| US-5276055-A | Antimycotic agents | MERCK & CO., INC. (US) | 1994-01-04 | — | — | US | disclosed |
| US-5136109-A | PROCESS FOR PREPARING 2,4-DICHLORO-3-ALKYL-6-NITROPHENOLS | TAOKA CHEMICAL COMPANY, LTD. (JP) | 1992-08-04 | — | — | US | disclosed |
| EP-0473464-A1 | Process for preparing 2-4-dichloro-3-alkyl-6-nitrophenols | TAOKA CHEMICAL CO., LTD (JP) | 1992-03-04 | — | — | EP | disclosed |
| US-5012015-A | Nitrading a trichlorobenzene with mixed acid, hydrolysis | DAIEI CHEMICAL CO., LTD. (JP) | 1991-04-30 | — | — | US | disclosed |
| EP-0175151-B1 | 2,4-DICHLORO-3-ALKYL-6-NITROPHENOLS AND PROCESS FOR THEIR PREPARATION | BAYER AG (DE) | 1989-01-18 | — | — | EP | disclosed |
| US-4670608-A | CATALYTIC CHLORINATION OF 1-ALKYL-4-NITROBENZENE | BAYER AKTIENGESELLSCHAFT (DE) | 1987-06-02 | — | — | US | disclosed |
| EP-0175151-A1 | 2,4-Dichloro-3-alkyl-6-nitrophenols and process for their preparation | BAYER AG (DE) | 1986-03-26 | — | — | EP | disclosed |