Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 3/20 | 0.47 |
| ▸ | ELANE | P08246 | 14/20 | 0.41 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30560160 | 1.00 | DHODH (0.47) | DHODHELANECYP17A1CYP1A2MEN1 | |
| SCHEMBL950583 | 0.92 | DHODH (0.42) | DHODHELANECYP17A1CYP1A2HPGD | |
| SCHEMBL950217 | 0.90 | DHODH (0.41) | DHODHELANEKMT2A | |
| SCHEMBL29598524 | 0.90 | DHODH (0.43) | DHODHELANECYP17A1CYP1A2POLB | |
| SCHEMBL30560159 | 0.90 | DHODH (0.43) | DHODHELANECYP17A1CYP1A2 | |
| SCHEMBL21822337 | 0.90 | DHODH (0.43) | DHODHELANECYP17A1CYP1A2 | |
| SCHEMBL12528168 | 0.90 | DHODH (0.43) | DHODHELANECYP17A1CYP1A2MEN1 | |
| SCHEMBL465839 | 0.90 | DHODH (0.43) | DHODHELANECYP17A1CYP1A2POLB | |
| SCHEMBL951196 | 0.89 | DHODH (0.41) | DHODHELANESMN1; SMN2 | |
| SCHEMBL959396 | 0.89 | DHODH (0.44) | DHODHCYP17A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3632911-B1 | METHOD FOR PREPARING ISOXAZINONE COMPOUND AND APPLICATION THEREOF | ZHEJIANG ZHUJI UNITED CHEMICALS CO LTD (CN) | 2023-08-09 | — | — | EP | disclosed |
| US-11299499-B2 | Preparation method and application of isoxazinone compounds | Zhejiang Zhuji United Chemicals Co., Ltd. (CN) | 2022-04-12 | — | — | US | disclosed |
| CN-107033135-B | Method for preparing isooxazinone compound and application thereof | 浙江省诸暨合力化学对外贸易有限公司 | 2020-09-11 | — | — | CN | disclosed |
| US-20200109152-A1 | PREPARATION METHOD AND APPLICATION OF ISOXAZINONE COMPOUNDS | Zhejiang Zhuji United Chemicals Co., Ltd. (CN) | 2020-04-09 | — | — | US | disclosed |
| EP-3632911-A1 | METHOD FOR PREPARING ISOXAZINONE COMPOUND AND APPLICATION THEREOF | Zhejiang Zhuji United Chemicals Co., Ltd (CN) | 2020-04-08 | — | — | EP | disclosed |
| US-20170015649-A1 | N-Thio-anthranilamid compounds and their use as pesticides | BASF SE (DE) | 2017-01-19 | — | — | US | disclosed |
| US-9365543-B2 | N-Thio-anthranilamid compounds and their use as pesticides | BASF SE | 2016-06-14 | — | — | US | disclosed |
| US-20150353523-A1 | N-Thio-anthranilamid compounds and their use as pesticides | BASF SE (DE) | 2015-12-10 | — | — | US | disclosed |
| US-9056853-B2 | N-Thio-anthranilamid compounds and their use as pesticides | BASF SE (DE) | 2015-06-16 | — | — | US | disclosed |
| US-20140378458-A1 | N-Thio-anthranilamid compounds and their use as pesticides | BASF SE (DE) | 2014-12-25 | — | — | US | disclosed |
| EP-1937664-B1 | HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME | SUMITOMO CHEMICAL CO (JP) | 2011-06-15 | — | — | EP | disclosed |
| US-20110071291-A1 | HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME | IKEGAMI HIROSHI | 2011-03-24 | — | — | US | disclosed |
| US-7867949-B2 | Hydrazide compound and pesticidal use of the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-01-11 | — | — | US | disclosed |
| EP-2251336-A1 | Hydrazide compounds as intermediates of pesticides | Sumitomo Chemical Company, Limited (JP) | 2010-11-17 | — | — | EP | disclosed |
| US-20090181956-A1 | Hydrazide Compound and Pesticidal Use of the Same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-07-16 | — | — | US | disclosed |
| US-20080221168-A1 | Methyl-phenyl-sulfamoyl-N-(5-bromo-2-(3-chloro-pyridin-2-yl)-2H-pyrazole-3-carboxylic acid (2-carbamoyl-6-methyl-phenyl))-amide | BASF AKTIENGESELLSCHAFT (DE) | 2008-09-11 | — | — | US | disclosed |
| EP-1904475-A1 | N-THIO-ANTHRANILAMID COMPOUNDS AND THEIR USE AS PESTICIDES | BASF SE (DE) | 2008-04-02 | — | — | EP | disclosed |
| WO-2007043677-A9 | HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME | SUMITOMO CHEMICAL CO (JP) | 2007-06-07 | — | — | WO | disclosed |
| WO-2007043677-A1 | HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-04-19 | — | — | WO | disclosed |
| WO-2007006670-A1 | N-THIO-ANTHRANILAMID COMPOUNDS AND THEIR USE AS PESTICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2007-01-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221168-A1 | Methyl-phenyl-sulfamoyl-N-(5-bromo-2-(3-chloro-pyridin-2-yl)-2H-pyrazole-3-carboxylic acid (2-carbamoyl-6-methyl-phenyl))-amide | AADAC, AAAS, ACMSD | DHODH 2613/4885ELANE 752/4885CYP17A1 4043/4885 |
| US-20140378458-A1 | N-Thio-anthranilamid compounds and their use as pesticides | NAT1, AAAS, ACHE | DHODH 1193/4885ELANE 719/4885CYP17A1 2971/4885 |
| US-20110071291-A1 | HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME | ACHE, H1-2, H1-0 | DHODH 771/4885ELANE 2684/4885CYP17A1 2438/4885 |
| US-11299499-B2 | Preparation method and application of isoxazinone compounds | NISCH, SI, DAO | DHODH 240/4885ELANE 3450/4885CYP17A1 152/4885 |
| US-20200109152-A1 | PREPARATION METHOD AND APPLICATION OF ISOXAZINONE COMPOUNDS | NISCH, SI, DAO | DHODH 240/4885ELANE 3450/4885CYP17A1 152/4885 |
| US-20170015649-A1 | N-Thio-anthranilamid compounds and their use as pesticides | NAT1, AAAS, ACHE | DHODH 1193/4885ELANE 719/4885CYP17A1 2971/4885 |
| US-20150353523-A1 | N-Thio-anthranilamid compounds and their use as pesticides | NAT1, AAAS, ACHE | DHODH 1193/4885ELANE 719/4885CYP17A1 2971/4885 |
| US-20090181956-A1 | Hydrazide Compound and Pesticidal Use of the Same | ACHE, DDT, CAT | DHODH 284/4885ELANE 2228/4885CYP17A1 1452/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.