SCHEMBL959396

SCHEMBL959396

Cc1cc(I)cc2c(=O)oc(-c3cc(Br)nn3-c3ncccc3Cl)nc12

nearest known ligand 0.44

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ DHODH Q02127 3/20 0.44
▸ PARP4 Q9UKK3 1/20 0.33
▸ CYP17A1 P05093 1/20 0.33
▸ CYP1A2 P05177 1/20 0.33
▸ C1R P00736 1/20 0.30
▸ TRPV1 Q8NER1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30466603 1.00 DHODH (0.44) DHODHPARP4CYP17A1CYP1A2C1R
SCHEMBL30560159 0.92 DHODH (0.43) DHODHPARP4CYP17A1CYP1A2TRPV1
SCHEMBL21822337 0.92 DHODH (0.43) DHODHPARP4CYP17A1CYP1A2TRPV1
SCHEMBL29598524 0.92 DHODH (0.43) DHODHCYP17A1CYP1A2TRPV1
SCHEMBL12528168 0.92 DHODH (0.43) DHODHPARP4CYP17A1CYP1A2TRPV1
SCHEMBL465839 0.92 DHODH (0.43) DHODHCYP17A1CYP1A2TRPV1
SCHEMBL28712183 0.91 DHODH (0.38) DHODHPARP4C1R
SCHEMBL959838 0.91 DHODH (0.35) DHODHPARP4CYP17A1CYP1A2C1R
SCHEMBL29215033 0.89 DHODH (0.36) DHODHPARP4CYP17A1CYP1A2
SCHEMBL30234123 0.89 DHODH (0.36) DHODHPARP4CYP17A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023110710-A1 METHOD FOR CONTROLLING DIAMIDE RESISTANT PESTS & COMPOUNDS THEREFOR SYNGENTA CROP PROTECTION AG (CH) 2023-06-22 — — WO disclosed
WO-2023110710-A1 METHOD FOR CONTROLLING DIAMIDE RESISTANT PESTS & COMPOUNDS THEREFOR SYNGENTA CROP PROTECTION AG (CH) 2023-06-22 — — WO disclosed
WO-2023079569-A1 A PROCESS FOR PREPARING BENZOXAZINONE COMPOUNDS TAGROS CHEMICALS INDIA PVT. LTD (IN) 2023-05-11 — — WO disclosed
EP-3141545-A1 POLYSUBSTITUTED PYRIDYLPYRAZOLE AMIDE AND PREPARATION METHOD AND USE THEREOF Zhaoqing Zhenge Biological Technology Co., Ltd. (CN) 2017-03-15 — — EP disclosed
US-9301529-B2 Polysubstituted pyridyl pyrazolecarboxamide and preparation method and use thereof ZHAOQING ZHENGE BIOLOGICAL TECHNOLOGY CO., LTD (CN) 2016-04-05 — — US disclosed
US-20150322037-A1 POLYSUBSTITUTED PYRIDYL PYRAZOLECARBOXAMIDE AND PREPARATION METHOD AND USE THEREOF ZHAOQING ZHENGE BIOLOGICAL TECHNOLOGY CO., LTD 2015-11-12 — — US disclosed
US-9161540-B2 Cyano anthranilamide insecticides E I DU PONT DE NEMOURS AND COMPANY (US) 2015-10-20 — — US disclosed
US-20150094474-A1 AGRICULTURAL CHEMICALS REDAG CROP PROTECTION LTD (GB) 2015-04-02 — — US disclosed
US-20150094474-A1 AGRICULTURAL CHEMICALS REDAG CROP PROTECTION LTD (GB) 2015-04-02 — — US disclosed
WO-2013136073-A1 AGRICULTURAL CHEMICALS REDX PHARMA LIMITED (GB) 2013-09-19 — — WO disclosed
EP-2264022-A1 Cyano anthranilamide insecticides E. I. du Pont de Nemours and Company (US) 2010-12-22 — — EP disclosed
US-20090104145-A1 Mixtures of Anthranilamide Invertebrate Pest Control Agents E. I. DU PONT DE NEMOURS AND COMPANY 2009-04-23 — — US disclosed
EP-1771070-B1 MIXTURES OF ANTHRANILAMIDE INVERTEBRATE PEST CONTROL AGENTS DU PONT (US) 2009-02-04 — — EP disclosed
US-20070264299-A1 Cyano anthranilamide insecticides FMC CORPORATION 2007-11-15 — — US disclosed
US-7247647-B2 Cyano anthranilamide insecticides E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-07-24 — — US disclosed
EP-1771070-A1 MIXTURES OF ANTHRANILAMIDE INVERTEBRATE PEST CONTROL AGENTS E.I. DUPONT DE NEMOURS AND COMPANY (US) 2007-04-11 — — EP disclosed
WO-2006068669-A1 MIXTURES OF ANTHRANILAMIDE INVERTEBRATE PEST CONTROL AGENTS E.I. DUPONT DE NEMOURS AND COMPANY (US) 2006-06-29 — — WO disclosed
US-20060111403-A1 Cyano anthranilamide insecticides FMC CORPORATION 2006-05-25 — — US disclosed
EP-1599463-A1 CYANO ANTHRANILAMIDE INSECTICIDES E.I. du Pont de Nemours and Company (US) 2005-11-30 — — EP disclosed
WO-2004067528-A1 CYANO ANTHRANILAMIDE INSECTICIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 2004-08-12 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150094474-A1 AGRICULTURAL CHEMICALS DDT, SQOR, GPX4 DHODH 81/4885PARP4 3418/4885CYP17A1 911/4885
US-20060111403-A1 Cyano anthranilamide insecticides C1S, C5, CBR3 DHODH 1074/4885PARP4 4483/4885CYP17A1 3340/4885
US-20150322037-A1 POLYSUBSTITUTED PYRIDYL PYRAZOLECARBOXAMIDE AND PREPARATION METHOD AND USE THEREOF PFAS, CYP3A5, PNPO DHODH 932/4885PARP4 2795/4885CYP17A1 955/4885
US-20090104145-A1 Mixtures of Anthranilamide Invertebrate Pest Control Agents NME4, NLN, STOM DHODH 717/4885PARP4 4632/4885CYP17A1 1230/4885
US-20070264299-A1 Cyano anthranilamide insecticides C1S, CBR3, C5 DHODH 1499/4885PARP4 4397/4885CYP17A1 3841/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback