Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.76 |
| ▸ | MRGPRX2 | Q96LB1 | 2/20 | 0.76 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.63 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Morphine Glucuronide SCHEMBL8410898 | 1.00 | OPRM1 (0.76) | OPRM1MRGPRX2OPRD1OPRK1 | |
| SCHEMBL8409388 | 0.92 | MRGPRX2 (0.77) | OPRM1MRGPRX2OPRD1OPRK1 | |
| Morphine Glucuronide SCHEMBL13267437 | 0.87 | OPRM1 (1.00) | OPRM1MRGPRX2OPRD1OPRK1 | |
| Morphine Glucuronide SCHEMBL13268600 | 0.87 | OPRM1 (1.00) | OPRM1MRGPRX2OPRD1OPRK1 | |
| Morphine Glucuronide SCHEMBL12082244 | 0.87 | OPRM1 (1.00) | OPRM1MRGPRX2OPRD1OPRK1 | |
| Morphine Glucuronide SCHEMBL17302928 | 0.87 | OPRM1 (1.00) | OPRM1MRGPRX2OPRD1OPRK1 | |
| Morphine Glucuronide SCHEMBL1743681 | 0.87 | OPRM1 (1.00) | OPRM1MRGPRX2OPRD1OPRK1 | |
| Morphine Glucuronide SCHEMBL13245908 | 0.87 | OPRM1 (1.00) | OPRM1MRGPRX2OPRD1OPRK1 | |
| Morphine Glucuronide SCHEMBL6754812 | 0.87 | OPRM1 (1.00) | OPRM1MRGPRX2OPRD1OPRK1 | |
| Morphine Glucuronide SCHEMBL152647 | 0.87 | OPRM1 (1.00) | OPRM1MRGPRX2OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5908927-A | Synthesis of deuterated opiate glucuronides | HIGH STANDARD PRODUCTS CORPORATION (US) | 1999-06-01 | — | — | US | claimed |
| US-5908927-A | Synthesis of deuterated opiate glucuronides | HIGH STANDARD PRODUCTS CORPORATION (US) | 1999-06-01 | — | — | US | disclosed |