SCHEMBL8409388

[2H]O[C@]1([2H])[C@@H](O)[C@H](O)[C@@H](C(=O)O)O[C@@]1([2H])O[C@H]1C=C[C@H]2[C@H]3Cc4ccc(OC)c5c4[C@@]2(CCN3C)[C@H]1O5

nearest known ligand 0.77

Predicted protein targets (top 7)

	gene	UniProt	supporting neighbours	confidence
▸	MRGPRX2	Q96LB1	4/20	0.77

▸	OPRM1	P35372	11/20	0.64

▸	OPRK1	P41145	7/20	0.64

▸	OPRD1	P41143	3/20	0.64

▸	ADRB1	P08588	1/20	0.59

▸	PDE4D	Q08499	1/20	0.59

▸	PDE3A	Q14432	1/20	0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Morphine Glucuronide SCHEMBL8411986	0.92	OPRM1 (0.76)	MRGPRX2OPRM1OPRK1OPRD1
Morphine Glucuronide SCHEMBL8410898	0.92	OPRM1 (0.76)	MRGPRX2OPRM1OPRK1OPRD1
SCHEMBL1261490	0.87	MRGPRX2 (1.00)	MRGPRX2OPRM1OPRK1OPRD1ADRB1
SCHEMBL8409352	0.87	MRGPRX2 (1.00)	MRGPRX2OPRM1OPRK1OPRD1ADRB1
SCHEMBL6753388	0.87	MRGPRX2 (1.00)	MRGPRX2OPRM1OPRK1OPRD1ADRB1
Morphine 3-Glucuronide SCHEMBL8412630	0.86	OPRM1 (0.62)	MRGPRX2OPRM1OPRK1OPRD1ADRB1
Morphine 3-Glucuronide SCHEMBL8409700	0.86	OPRM1 (0.62)	MRGPRX2OPRM1OPRK1OPRD1ADRB1
SCHEMBL2171816	0.81	MRGPRX2 (0.89)	MRGPRX2OPRM1OPRK1OPRD1
SCHEMBL3017103	0.81	MRGPRX2 (0.89)	MRGPRX2OPRM1OPRK1OPRD1
SCHEMBL11778970	0.81	OPRM1 (0.89)	MRGPRX2OPRM1OPRK1OPRD1ADRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-5908927-A	Synthesis of deuterated opiate glucuronides	HIGH STANDARD PRODUCTS CORPORATION (US)	1999-06-01	—	—	US	claimed
US-5908927-A	Synthesis of deuterated opiate glucuronides	HIGH STANDARD PRODUCTS CORPORATION (US)	1999-06-01	—	—	US	disclosed