Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | HTR5A | P47898 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8413528 | 0.86 | TP53 (0.53) | TP53HTR1ADRD2DRD4HTR2A | |
| SCHEMBL8413788 | 0.84 | HTR2C (0.42) | HTR2AHTR2CKDM4EALDH1A1 | |
| SCHEMBL8413093 | 0.84 | L3MBTL1 (0.39) | TP53HTR1AADRA2ADRD2ADRA2B | |
| SCHEMBL8410491 | 0.78 | TP53 (0.40) | TP53HTR1AADRA2ADRD2ADRA2B | |
| SCHEMBL8412328 | 0.74 | NPC1 (0.41) | TP53HTR1AADRA2ADRD2ADRA2B | |
| SCHEMBL8413134 | 0.74 | TP53 (0.39) | TP53HTR1AADRA2ADRD2ADRA2B | |
| SCHEMBL8413715 | 0.74 | TP53 (0.40) | TP53HTR1AADRA2ADRD2ADRA2B | |
| SCHEMBL8413761 | 0.71 | HTR7 (0.39) | TP53HTR1AADRA2ADRD2ADRA2B | |
| SCHEMBL8410169 | 0.71 | HTR2C (0.47) | DRD2HTR2AHTR2CHTR7KDM4E | |
| SCHEMBL8412314 | 0.70 | CYP2D6 (0.44) | DRD2ALDH1A1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5874429-A | ANTIISCHEMIC AGENTS; CEREBROVASCULAR DISORDERS; CIRCULATORY IDSORDERS | SUNTORY LIMITED (JP) | 1999-02-23 | — | — | US | disclosed |