Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 6/20 | 0.40 |
| ▸ | DRD4 | P21917 | 2/20 | 0.40 |
| ▸ | DRD5 | P21918 | 2/20 | 0.40 |
| ▸ | DRD3 | P35462 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 4/20 | 0.40 |
| ▸ | HTR2A | P28223 | 3/20 | 0.40 |
| ▸ | HTR7 | P34969 | 3/20 | 0.40 |
| ▸ | HTR6 | P50406 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8412378 | 0.86 | TP53 (0.45) | TP53MAPTKDM4EALDH1A1DRD2 | |
| SCHEMBL8413715 | 0.83 | TP53 (0.40) | TP53KDM4EALDH1A1DRD2DRD4 | |
| SCHEMBL8410169 | 0.82 | HTR2C (0.47) | KDM4EALDH1A1DRD2HTR2AHTR7 | |
| SCHEMBL8412328 | 0.77 | NPC1 (0.41) | TP53MAPTALDH1A1DRD2DRD4 | |
| SCHEMBL8410491 | 0.77 | TP53 (0.40) | TP53MAPTDRD2DRD4DRD3 | |
| SCHEMBL8413134 | 0.75 | TP53 (0.39) | TP53MAPTALDH1A1DRD2DRD4 | |
| SCHEMBL8413761 | 0.74 | HTR7 (0.39) | TP53MAPTALDH1A1DRD2DRD4 | |
| SCHEMBL8413371 | 0.74 | TYR (0.41) | MAPTKDM4EALDH1A1DRD2HTR1A | |
| SCHEMBL8413093 | 0.74 | L3MBTL1 (0.39) | TP53MAPTKDM4EALDH1A1DRD2 | |
| SCHEMBL8410575 | 0.73 | HTR7 (0.38) | TP53DRD2DRD4DRD3HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5874429-A | ANTIISCHEMIC AGENTS; CEREBROVASCULAR DISORDERS; CIRCULATORY IDSORDERS | SUNTORY LIMITED (JP) | 1999-02-23 | — | — | US | disclosed |