Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 5/20 | 0.53 |
| ▸ | AGTR2 | P50052 | 4/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.45 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8411067 | 0.90 | AGTR1 (0.54) | AGTR1AGTR2ACHELTB4R2F2RL3 | |
| SCHEMBL8327497 | 0.90 | AGTR1 (0.56) | AGTR1AGTR2 | |
| SCHEMBL8327498 | 0.83 | ICMT (0.45) | AGTR1AGTR2F2RL3HDAC10HDAC6 | |
| SCHEMBL8414576 | 0.81 | AGTR1 (0.51) | AGTR1AGTR2ACHELTB4R2 | |
| SCHEMBL8412385 | 0.80 | AGTR1 (0.50) | AGTR1AGTR2ACHECNR2 | |
| SCHEMBL8410082 | 0.79 | AGTR1 (0.49) | AGTR1AGTR2ACHELTB4R2 | |
| SCHEMBL8410857 | 0.79 | AGTR1 (0.49) | AGTR1AGTR2ACHELTB4R2 | |
| SCHEMBL8325939 | 0.79 | AGTR1 (0.57) | AGTR1AGTR2 | |
| SCHEMBL8410125 | 0.79 | AGTR1 (0.50) | AGTR1AGTR2ACHELTB4R2SLC6A3 | |
| SCHEMBL8502142 | 0.77 | ACHE (0.54) | AGTR1AGTR2ACHELTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5985894-A | USEFUL IN THE TREATMENT OF CARDIOVASCULAR ILLNESSES | HOECHST MARION ROUSSEL (FR) | 1999-11-16 | — | — | US | disclosed |