Phosphoric Acid — predicted protein targets

Known targets — ChEMBL curated mechanism

ADRA1A ADRA1B ADRA1D ADRB1 ADRB2 ADRB3 CYP11B1 DPP4 FGFR1 FGFR2 FGFR3 FGFR4 HRH1 JAK1 JAK2 JAK3 KCNA1 KCNA10 KCNA2 KCNA3 KCNA4 KCNA5 KCNA6 KCNA7 KCNB1 KCNB2 KCNC1 KCNC2 KCNC3 KCNC4 KCND1 KCND2 KCND3 KCNF1 KCNG1 KCNG2 KCNG3 KCNG4 KCNH1 KCNH2 KCNH3 KCNH4 KCNH5 KCNH6 KCNH7 KCNH8 KCNQ1 KCNQ2 KCNQ3 KCNQ4 KCNQ5 KCNS1 KCNS2 KCNS3 KCNV1 KCNV2 KDR KIT NA OPRD1 OPRK1 OPRM1 P PDGFRB PIK3CD SCN10A SCN11A SCN1A SCN2A SCN3A SCN4A SCN5A SCN7A SCN8A SCN9A SMO TYK2 pol rplA rplB rplC rplD rplE rplF rplJ rplK rplL rplM rplN rplO rplP rplQ rplR rplS rplT rplU rplV rplW rplX rplY rpmA rpmB rpmC rpmD rpmE rpmF rpmG rpmH rpmI rpmJ rpsA rpsB rpsC rpsD rpsE rpsF rpsG rpsH rpsI rpsJ rpsK rpsL rpsM rpsN rpsO rpsP rpsQ rpsR rpsS rpsT rpsU ykgM ykgO

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

	gene	UniProt	supporting neighbours	confidence
▸	ADRA1A known ✓	P35348	1/20	0.38

▸	KCNH2 known ✓	Q12809	1/20	0.38

▸	KCNA1 known ✓	Q09470	1/20	0.35

▸	SLC22A1	O15245	3/20	0.55

▸	DNM1	Q05193	5/20	0.52

▸	SLC22A2	O15244	1/20	0.48

▸	TSHR	P16473	2/20	0.43

▸	ALDH1A1	P00352	1/20	0.43

▸	TP53	P04637	1/20	0.43

▸	CYP3A4	P08684	1/20	0.43

▸	ALOX15	P16050	1/20	0.43

▸	ALOX12	P18054	1/20	0.43

▸	SMN1; SMN2	Q16637	1/20	0.43

▸	HIF1A	Q16665	1/20	0.43

▸	HSD17B10	Q99714	1/20	0.43

▸	LMNA	P02545	1/20	0.38

▸	ESR1	P03372	1/20	0.38

▸	ADORA3	P0DMS8	1/20	0.38

▸	CDC25A	P30304	1/20	0.38

▸	AGTR1	P30556	1/20	0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Phosphoric Acid SCHEMBL2373400	0.95	DNM1 (0.61)	SLC22A1DNM1SLC22A2TSHRALDH1A1
Phosphoric Acid SCHEMBL31669648	0.95	DNM1 (0.59)	SLC22A1DNM1SLC22A2TSHRALDH1A1
Phosphoric Acid SCHEMBL7641438	0.95	SLC22A1 (0.55)	SLC22A1DNM1SLC22A2TSHRALDH1A1
Phosphoric Acid SCHEMBL10632843	0.93	SLC22A1 (0.48)	SLC22A1DNM1SLC22A2TSHRALDH1A1
Tetrabuthylammonium SCHEMBL19834900	0.89	SLC22A1 (0.71)	SLC22A1DNM1SLC22A2TSHRALDH1A1
Tetrabuthylammonium SCHEMBL49814	0.89	SLC22A1 (0.71)	SLC22A1DNM1SLC22A2TSHRALDH1A1
SCHEMBL20543356	0.88	DNM1 (0.52)	SLC22A1DNM1SLC22A2TSHRALDH1A1
Phosphoric Acid SCHEMBL1203422	0.87	DNM1 (0.71)	SLC22A1DNM1SLC22A2TSHRALDH1A1
Phosphoric Acid SCHEMBL8911224	0.87	SLC22A1 (0.52)	SLC22A1DNM1SLC22A2TSHRALDH1A1
Tetrabuthylammonium SCHEMBL3141779	0.86	SLC22A1 (0.67)	SLC22A1DNM1SLC22A2TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-0931856-A2	Process for reductive coupling in an electrolytic cell with a cathode comprising an iron-based substrate and a lead-based coating	BASF AKTIENGESELLSCHAFT (DE)	1999-07-28	—	—	EP	disclosed
US-5593557-A	ELECTROHYDRODIMERIZATION OF ACRYLONITRILE	BASF AKTIENGESELLSCHAFT (DE)	1997-01-14	—	—	US	disclosed
EP-0635587-A1	Electrode comprising an iron containing substrate and a lead containing coating	BASF Aktiengesellschaft (DE)	1995-01-25	—	—	EP	disclosed
US-4789442-A	ELECTROHYDRODIMERIZATION OF ACRYLONITRILE; CORROSION RESISTANCE	ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP)	1988-12-06	—	—	US	disclosed
EP-0270390-A2	A method for producing adiponitrile	Asahi Kasei Kogyo Kabushiki Kaisha (JP)	1988-06-08	—	—	EP	disclosed