SCHEMBL841397

SCHEMBL841397

CC(C)c1cc(C(C)C)c(C(Br)C=O)c(C(C)C)c1

nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
FABP4 P15090 3/20 0.42
FABP3 P05413 2/20 0.42
FABP5 Q01469 1/20 0.41
GABRA1 P14867 1/20 0.39
GABRB2 P47870 1/20 0.39
TYR P14679 2/20 0.33
ALDH1A1 P00352 1/20 0.33
RARG P13631 1/20 0.31
RXRA P19793 1/20 0.31
PPARG P37231 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL861863 0.84 GABRA1 (0.47) GABRA1
SCHEMBL21575508 0.76 FABP4 (0.42) FABP4FABP3FABP5GABRA1GABRB2
SCHEMBL27898737 0.76 FABP3 (0.39) FABP4FABP3FABP5GABRA1GABRB2
SCHEMBL9064395 0.73 GABRA1 (0.52) FABP4FABP3FABP5GABRA1GABRB2
SCHEMBL2590567 0.70 FABP4 (0.52) FABP4FABP3FABP5GABRA1GABRB2
SCHEMBL1505157 0.70 TYR (0.54) TYRALDH1A1
SCHEMBL9369688 0.68 FABP4 (0.56) FABP4FABP3FABP5GABRA1GABRB2
SCHEMBL10753709 0.67 GABRA1 (0.52) FABP4FABP3FABP5GABRA1GABRB2
SCHEMBL27561857 0.67 FABP4 (0.45) FABP4FABP3FABP5GABRA1GABRB2
SCHEMBL339679 0.66 GABRA1 (0.50) FABP4FABP3FABP5GABRA1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3569606-B1 METAL COMPLEXES OF CYCLOMETALLATED IMIDAZO (1,2-F)PHENANTHRIDINE AND DIIMIDAZO (1,2-A; 1', 2'-C)QUINAZOLINE LIGANDS AND ISOELECTRONIC AND BENZANNULATED ANALOGS THEREOF UNIVERSAL DISPLAY CORP (US) 2022-01-05 EP disclosed
US-10978649-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-04-13 US disclosed
US-20200350504-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-11-05 US disclosed
US-10749121-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-08-18 US disclosed
EP-3569606-A1 METAL COMPLEXES OF CYCLOMETALLATED IMIDAZO (1,2-F)PHENANTHRIDINE AND DIIMIDAZO (1,2-A; 1', 2'-C)QUINAZOLINE LIGANDS AND ISOELECTRONIC AND BENZANNULATED ANALOGS THEREOF Universal Display Corporation (US) 2019-11-20 EP disclosed
US-20190341563-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-11-07 US disclosed
US-10403831-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-09-03 US disclosed
EP-2399922-B1 Metal complexes of cyclometallated imidazo(1,2-f) phenanthridine and diimidazo(1,2-A;1',2'-C)quinazoline ligands and isoelectronic and benzannulated analogs therof UNIVERSAL DISPLAY CORP (US) 2019-06-26 EP disclosed
EP-2399922-B1 Metal complexes of cyclometallated imidazo(1,2-f) phenanthridine and diimidazo(1,2-A;1',2'-C)quinazoline ligands and isoelectronic and benzannulated analogs therof UNIVERSAL DISPLAY CORP (US) 2019-06-26 EP disclosed
EP-1981898-B2 Metal complexes of imidazo[1,2-f]phenanthridine ligands for use in OLED devices UNIVERSAL DISPLAY CORP (US) 2019-04-10 EP disclosed
WO-2008156879-A1 BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2008-12-24 WO disclosed
WO-2008156879-A1 BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2008-12-24 WO disclosed
US-20080297033-A1 BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS UNIVERSAL DISPLAY CORPORATION 2008-12-04 US disclosed
US-20080297033-A1 BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS UNIVERSAL DISPLAY CORPORATION 2008-12-04 US disclosed
US-20080297033-A1 BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS UNIVERSAL DISPLAY CORPORATION 2008-12-04 US disclosed
EP-1981898-A2 METAL COMPLEXES OF CYCLOMETALLATED IMIDAZOÝ1,2-f¨PHENANTHRIDINE AND DIIMIDAZOÝ1,2-A:1',2'-C¨QUINAZOLINE LIGANDS AND ISOELECTRONIC AND BENZANNULATED ANALOGS THEREOF Universal Display Corporation (US) 2008-10-22 EP disclosed
WO-2007095118-A2 METAL COMPLEXES OF CYCLOMETALLATED IMIDAZO[1,2-f]PHENANTHRIDINE AND DIIMIDAZO[1,2-A:1',2'-C]QUINAZOLINE LIGANDS AND ISOELECTRONIC AND BENZANNULATED ANALOGS THEREOF UNIVERSAL DISPLAY CORPORATION (US) 2007-08-23 WO disclosed
US-20070190359-A1 Metal complexes of cyclometallated imidazo[1,2-ƒ]phenanthridine and diimidazo[1,2-a:1',2'-c]quinazoline ligands and isoelectronic and benzannulated analogs thereof UNIVERSAL DISPLAY CORPORATION 2007-08-16 US disclosed
US-20070190359-A1 Metal complexes of cyclometallated imidazo[1,2-ƒ]phenanthridine and diimidazo[1,2-a:1',2'-c]quinazoline ligands and isoelectronic and benzannulated analogs thereof UNIVERSAL DISPLAY CORPORATION 2007-08-16 US disclosed
US-20070190359-A1 Metal complexes of cyclometallated imidazo[1,2-ƒ]phenanthridine and diimidazo[1,2-a:1',2'-c]quinazoline ligands and isoelectronic and benzannulated analogs thereof UNIVERSAL DISPLAY CORPORATION 2007-08-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190341563-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES LIG1, L1CAM, LIG3 FABP4 3415/4885FABP3 2541/4885FABP5 1792/4885
US-10978649-B2 Organic electroluminescent materials and devices NR2C2, NR2E3, NCOA2 FABP4 3453/4885FABP3 3163/4885FABP5 3017/4885
US-20080297033-A1 BLUE PHOSPHORESCENT IMIDAZOPHENANTHRIDINE MATERIALS IK, CRY1, MAP1LC3C FABP4 4068/4885FABP3 3251/4885FABP5 2337/4885
US-10749121-B2 Organic electroluminescent materials and devices LIG1, L1CAM, LIG3 FABP4 3415/4885FABP3 2541/4885FABP5 1792/4885
US-10403831-B2 Organic electroluminescent materials and devices LIG1, L1CAM, LIG3 FABP4 3415/4885FABP3 2541/4885FABP5 1792/4885
US-20200350504-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES NR2C2, NR2E3, NCOA2 FABP4 3453/4885FABP3 3163/4885FABP5 3017/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.