Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SI | P14410 | 1/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 4/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8413225 | 0.89 | ALDH1A1 (0.39) | MGAMGAASIMGAM2FAAH | |
| SCHEMBL9274578 | 0.89 | MGAM (0.41) | MGAMGAASIMGAM2 | |
| SCHEMBL5816002 | 0.87 | ALDH1A1 (0.38) | MGAMGAASIMGAM2FAAH | |
| SCHEMBL28203941 | 0.87 | ALDH1A1 (0.38) | MGAMGAASIMGAM2FAAH | |
| SCHEMBL27870049 | 0.85 | FAAH (0.33) | FAAHCNR1CNR2LMNA | |
| SCHEMBL10570400 | 0.84 | MGAM (0.44) | MGAMGAASIMGAM2FAAH | |
| SCHEMBL448064 | 0.82 | NAAA (0.38) | LMNA | |
| SCHEMBL17871680 | 0.82 | LMNA (0.44) | LMNA | |
| SCHEMBL6837511 | 0.81 | MGAM (0.55) | MGAMGAASIMGAM2FAAH | |
| SCHEMBL6438668 | 0.81 | MGAM (0.41) | MGAMGAASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0931820-A1 | Coating composition and its cured product | JSR Corporation (JP) | 1999-07-28 | — | — | EP | disclosed |
| US-5011848-A | Cardiovascular disorders, hypotensive agents | GLAXO, S.P.A. (IT) | 1991-04-30 | — | — | US | disclosed |
| US-4845109-A | VASODILATORS, HYPOTENSIVE AGENTS | MAKAROVA NATALYA V (SU) | 1989-07-04 | — | — | US | disclosed |
| US-4801599-A | CARDIOVASCULAR DISORDERS, HYPOTENSIVE AGENTS | GLAXO S.P.A. (IT) | 1989-01-31 | — | — | US | disclosed |
| US-4352800-A | ANTIBIOTICS, BLOOD | KYOTO YAKUHIN KYOGO KABUSHIKI KAISHA (JP) | 1982-10-05 | — | — | US | disclosed |
| US-4277465-A | ENAMINE DERIVATIVE | KYOTO YAKUHIN KOGYO KABUSHIKI KAISHA (JP) | 1981-07-07 | — | — | US | disclosed |
| EP-0009609-A2 | Adjuvant for promoting absorption of therapeutically active substances through the digestive tract, pharmaceutical composition comprising said adjuvant and process for preparing said pharmaceutical composition; enamine derivatives | KYOTO YAKUHIN KOGYO KABUSHIKI KAISHA (JP) | 1980-04-16 | — | — | EP | disclosed |
| US-4188395-A | 1,4-Dihydropyridine derivatives substituted in the 2 position, and their use as medicaments | BAYER AKTIENGESELLSCHAFT (DE) | 1980-02-12 | — | — | US | disclosed |
| US-3985758-A | 1,4-Dihydropyridine derivatives | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JA) | 1976-10-12 | — | — | US | disclosed |